20 Cooperstown beagles of known DL-A genotypes (B" dogs) were exposed to supralethal total body irradiation and received a bone marrow allograft from a DL-A identical donor (A" dog); the resulting chimeras have survived uneventfully for 882, 1466 days, with no evidence of secondary disease, and have been tolerant to kidney and skin allografts obtained from the donor of marrow. Treatment of "A" dogs with serum obtained from their long-term "B" chimeras had no significant effect upon the ability of the recipients to reject "B" skin allografts...
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189866 | PMC |
| http://dx.doi.org/10.1084/jem.142.1.120 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Extrapulmonary Pneumocystis jirovecii infection in an advanced HIV-infected patient: A case report and literature review.
BMC Infect Dis
March 2023
Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand.
Background: Pneumocystis jirovecii infection is the most common opportunistic infection that causes pneumonia in human immunodeficiency virus (HIV)-infected patients; however, extrapulmonary P. jirovecii infection is extremely rare after the use of antiretroviral therapy. Here, we present the second reported case of paraspinal mass caused by P.
View Article and Find Full Text PDFLipoprotein (a): a historical appraisal.
J Lipid Res
January 2017
Institute of Molecular Biology and Biochemistry, Medical University of Graz, A-8010 Graz, Austria
Initially, lipoprotein (a) [Lp(a)] was believed to be a genetic variant of lipoprotein (Lp)-B. Because its lipid moiety is almost identical to LDL, Lp(a) has been deliberately considered to be highly atherogenic. Lp(a) was detected in 1963 by Kare Berg, and individuals who were positive for this factor were called Lpa Lpa individuals were found more frequently in patients with coronary heart disease than in controls.
View Article and Find Full Text PDFEffects of daily almond consumption on cardiometabolic risk and abdominal adiposity in healthy adults with elevated LDL-cholesterol: a randomized controlled trial.
J Am Heart Assoc
January 2015
Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA (C.E.B., S.G.W., J.A.F., P.M.K.E.).
Background: Evidence consistently shows that almond consumption beneficially affects lipids and lipoproteins. Almonds, however, have not been evaluated in a controlled-feeding setting using a diet design with only a single, calorie-matched food substitution to assess their specific effects on cardiometabolic risk factors.
Methods And Results: In a randomized, 2-period (6 week/period), crossover, controlled-feeding study of 48 individuals with elevated LDL-C (149±3 mg/dL), a cholesterol-lowering diet with almonds (1.
The impact of hyperhomocysteinemia as a cardiovascular risk factor in the prediction of coronary heart disease.
Clin Chem Lab Med
November 2003
Department of Clinical Chemistry, Saarland Medical School, Homburg, Germany.
Coronary heart disease often occurs in the absence of traditional risk factors. Consequently, epidemiological studies exploring novel risk factors are necessary to improve the prediction of coronary heart disease. This study evaluated five promising markers of cardiovascular risk: homocysteine, C-reactive protein, fibrinogen, lipoprotein(a) (Lp(a)), free apolipoprotein(a) (apo(a)) and Lp(a) phenotypes.
View Article and Find Full Text PDFAcute mountain sickness; prophylactic benefits of antioxidant vitamin supplementation at high altitude.
High Alt Med Biol
May 2001
Health and Exercise Sciences, Research Laboratory, School of Applied Sciences, University of Glamorgan, Pontypridd, South Wales, UK.
Acute mountain sickness; prophylactic benefits of Free-radical-mediated damage to the blood-brain barrier may be implicated in the pathophysiology of acute mountain sickness (AMS). To indirectly examine this, we conducted a randomized double-blind placebo-controlled trial to assess the potentially prophylactic benefits of enteral antioxidant vitamin supplementation during ascent to high altitude. Eighteen subjects aged 35 +/- 10 years old were randomly assigned double-blind to either an antioxidant (n = 9) or placebo group (n = 9).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!