In-vitro synergistic activity of the combination of ampicillin and arbekacin against vancomycin-and high-level gentamicin-resistant Enterococcus faecium with the aph(2")-Id gene.

Diagn Microbiol Infect Dis

Research and Medical Service, John D Dingell VA Medical Center, and Division of Infectious Diseases, Wayne State University School of Medicine, Detroit, MI 48201, USA.

Published: August 2000

The combination of ampicillin plus arbekacin produced synergistic killing against 8 of 13 vancomycin-, ampicillin-, gentamicin-, and streptomycin-resistant Enterococcus faecium isolates that possess the high-level gentamicin resistance gene, aph(2")-Id. This combination may prove useful in treating infections caused by multiresistant enterococci.

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http://dx.doi.org/10.1016/s0732-8893(00)00155-3DOI Listing

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