AI Article Synopsis
- Systemic lupus erythematosus (SLE) is an autoimmune disorder that can affect multiple systems in the body, and there is limited research on its effects on the nervous system and eyes in children.
- The case of an 8-year-old patient with suspected SLE showcased symptoms like skin rash, joint pain, headaches, seizures, and papilledema due to obstructive hydrocephalus.
- The study highlights the need for careful monitoring and a collaborative approach to manage the significant neurological and psychiatric challenges that can arise in children with SLE.
Article Abstract
Background: Systemic lupus erythematosus (SLE) is an autoimmune, multisystem disorder with diverse manifestations. There are limited reports on the neuro-ophthalmic and neuropsychiatric findings in childhood SLE.
Case Report: An 8-year-old patient with suspected SLE with a history of skin rash, joint pain, transient hematologic abnormality, headaches, seizures, and psychosis, presented with papilledema secondary to acquired, obstructive hydrocephalus.
Discussion: SLE-related ocular and neuropsychiatric findings are reviewed. Proposed mechanisms for ocular and cerebral lupus include immune complex deposition, vascular thrombosis, and postinflammatory lesions.
Conclusion: The prevalent neurologic and neuropsychiatric complications of pediatric SLE require close follow-up and interdisciplinary management.
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| http://dx.doi.org/10.1097/00006324-200008000-00005 | DOI Listing |
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