We describe a case of culture-proven Brucella spondylitis in a 28-y-old Turkish male asylum seeker who had arrived to Norway 6 months earlier. Several diagnostic difficulties, including rapid in vitro growth and misidentification of the causative microorganism in biochemical gallery strip tests, resulted in late diagnosis.
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Quantifying research hotspots and trends in brucella spondylitis: a bibliometric analysis.
Front Surg
January 2025
Department of Orthopedic, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China.
Background: Human brucellosis is the most common bacterial zoonosis worldwide, with brucella spondylitis (BS) being one of its most severe forms, potentially leading to spinal deformity or paralysis. This study aims to provide a comprehensive overview of the current status and research trends in the BS field using bibliometric methods.
Methods: Publications on BS from January 1, 1980, to March 24, 2024, were retrieved from the Web of Science database.
Differences analysis between spinal tuberculosis and brucella spondylitis with preoperative non-invasive differential diagnosis.
Eur Spine J
January 2025
Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou, Gansu, 730000, China.
Objective: Spinal tuberculosis (STB) and Brucella spondylitis (BS) represent two types of granulomatous infections affecting the spine, which exhibit significant similarities that often result in misdiagnosis and overlooked diagnoses during preoperative evaluations. This study aims to identify non-invasive evaluative indicators that facilitate the differentiation between STB and BS.
Methods: This study conducted a retrospective collection of clinical features, laboratory tests, and imaging characteristics from 89 patients diagnosed with STB and 66 patients diagnosed with BS.
Comparison of the Effects of H37Rv and Infiltration on Tumor Necrosis Factor-Alpha and Interleukin-1 Beta Expression in Osteoblasts.
Surg Infect (Larchmt)
January 2025
First Clinical Medical College, Ningxia Medical University, Yinchuan, China.
This study aims to compare the expression levels of tumor necrosis factor-alpha (TNF-α) and interleukin-1 beta (IL-1β) in osteoblasts infiltrated with H37Rv (H37Rv) and to understand the differential bone destruction in spinal tuberculosis (STB) versus spondylitis (BS). Primary osteoblasts were isolated and cultured from the cranial bones of 2-5 days old mice and characterized by alkaline phosphatase (ALP) staining and alizarin red staining (ARS). H37Rv and were cultured to the logarithmic phase, and transfection solutions were prepared.
View Article and Find Full Text PDFProlonged fever in a 13-year-old girl misdiagnosed as Ochrobactrum spp. bacteremia-the pitfalls of diagnostic Brucella spondylitis in a non-endemic country.
Folia Microbiol (Praha)
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Department of Medical Microbiology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
Brucellosis is a zoonosis with non-specific clinical symptoms involving multiple systems and organs. Its prevalence is low in most of EU countries, which can lead to the difficulties in laboratory and clinical diagnostic. Due to its relationship to the Ochrobactrum spp.
View Article and Find Full Text PDFEpidemiology and laboratory testing of Brucella spondylitis.
Sci Rep
November 2024
Department of Spine Surgery, The 940th Hospital of Joint Logistics Support Force of Chinese PLA, Lanzhou, Gansu, China.
Article Synopsis
- The study focused on patients with Brucella spondylitis (BS), averaging around 52 years old, primarily affecting males, and linked to close contact with livestock and unpasteurized food.
- The diagnostic effectiveness of the Rose Bengal Test (RBT) and Standard Agglutination Test (SAT) was notably high at 94.6%, compared to a low blood culture positivity rate of 7.8%.
- Common symptoms included fever, back pain, and fatigue, with imaging showing the lumbar spine, especially L4/5, as frequently affected; after treatment, the recurrence rate was low at 3.0%.
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