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Background: Although revascularization is first-line therapy for chronic limb-threatening ischemia (CLTI), there are no established treatments for patients in whom revascularization is not (or is a poor) option, including CLTI that has responded poorly to revascularization. This study verified the efficacy of the Rheocarna, a novel apheresis device, for no-option CLTI or poor-response CLTI after revascularization.

Methods And Results: This multicenter retrospective observational study analyzed 221 patients (221 limbs) with no- or poor-option CLTI (mean [±SD] age 71±10 years; males, 70.

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LEANBH study: Device satisfaction study for the use of a novel connected home blood pressure system in pregnancy; a prospective cohort study.

Pregnancy Hypertens

January 2025

INFANT Research Centre, Cork, Ireland; Department of Obstetrics and Gynaecology, University College Cork, Cork, Ireland. Electronic address:

Objectives: To investigate patients' perspectives on using the LEANBH app (home Blood Pressure BP monitoring system) and the Microlife Watch BP home monitor in a tertiary maternity hospital setting during the COVID-19 pandemic.

Study Design: 134 Participants were asked to complete an anonymous usability questionnaire on their experience of LEANBH and the Microlife Watch. The questionnaire consisted of 5 background demographics, 9 items from the system usability scale (SUS), 14 items on the usability of the LEANBH app, and 6 on the acceptability of Microlife.

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Rationale: Previous studies evaluating the effect of continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea (OSA) on blood pressure (BP) showed variable results. Moreover, several studies recruited patients with normal or controlled BP, and compliance to antihypertensive drugs was not monitored. In addition, very few studies investigated central BP in this scenario.

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Background: There is still a significant population of patients with embolic stroke of Undetermined Source (ESUS) whose specific attributable cause of the stroke remains unknown.

Objectives: Our research aimed to assess clinical, electrocardiogram, laboratory, and echocardiographic parameters that may predict the propensity of paroxysmal atrial fibrillation (PAF).

Methods: We enrolled seventy-five ESUS patients who were in sinus rhythm at the time of stroke diagnosis to undergo in-hospital 7-day Holter monitoring, testing for Pro-BNP, and a standard echocardiographic examination.

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Costs and characteristics of admissions due to ambulatory care-sensitive conditions in children under one year of age in São Paulo, Brazil.

Cien Saude Colet

January 2025

Departamento de Odontologia Social, Faculdade de Odontologia de Piracicaba, Universidade Estadual de Campinas. Campinas SP Brasil.

This research aimed to estimate the direct costs and analyze the epidemiological aspects of ambulatory care-sensitive conditions (ACSC) in children under one year of age, São Paulo municipality, 2011-2022. Total and average costs were calculated according to ACSC diagnosis groups by components (early neonatal, late neonatal, and post-neonatal). The trend in ACSC rates was analyzed using Prais-Winsten generalized linear regression.

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