[Teratogens during pregnancy].

Objective: To sum up the knowledge of the influence of substances in the external environment on the development of the human embryo/fetus during exposure at various periods of intrauterine life.

Type Of Study: Summary.

Setting: Department of Obstetrics and Gynecology, 1st Faculty of Medicine, Charles University, Prague.

Methods: Compilation of data from scientific literature.

Results: An overview of the main groups of teratogenic substances among the physical, chemical, biological and metabolic teratogens. Their relationship to morphological malformations, anomalies and functional defects are described.

Conclusion: A summary of the principles/basics of care of a pregnant woman using medication before or during pregnancy and the possibility of evaluating the individual reproductive risk during preconception and prenatal exposure to teratogenic substances.