Enterococcus faecalis LC40 is an ampicillin-susceptible clinical isolate with high-level gentamicin resistance due to the aac(6')-Ie-aph(2")-Ia aminoglycoside resistance gene. The combination of ampicillin plus arbekacin reduced mean bacterial vegetation counts significantly more than ampicillin alone or ampicillin plus gentamicin in a rabbit model of aortic-valve endocarditis caused by E. faecalis LC40.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC90103 | PMC |
http://dx.doi.org/10.1128/AAC.44.9.2545-2546.2000 | DOI Listing |
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