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Acute Decompensated Valvular Disease in the Intensive Care Unit.
JACC Adv
December 2024
TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Acute decompensated valvular disease encompasses a group of complex and challenging conditions, which are often the primary reason for admission to the cardiac intensive care unit and can also complicate the management of other primary cardiac disorders. Critically ill patients with valvular disease also present unique diagnostic and management challenges. Historically, medical and percutaneous interventional therapies have been limited and surgery was the only definitive treatment; however, surgical risk can at times be prohibitive.
View Article and Find Full Text PDFDeceased Donor Infectious Diseases Testing and Antimicrobial Use: Surveys of Organ Procurement Organizations and Transplant Professionals.
Transpl Infect Dis
November 2024
Bethesda, Maryland, USA.
Background: Donor screening and antimicrobial management processes are inconsistent across organ procurement organizations (OPOs) and transplant centers. As part of a Controversies Conference addressing the evaluation and management of infectious diseases (ID) in deceased donors sponsored by the American Society of Transplantation (AST), two online pre-meeting surveys were developed to inform conference proceedings and assess current practices and opinions on donor screening and antimicrobial management.
Methods: Survey 1 addressed the current state of deceased donor ID testing, culture data communication, antimicrobial utilization, and involvement of transplant ID during donor management and was distributed to all 56 United States OPOs.
Echocardiographic Evaluation of Chronic Aortic Regurgitation: Comparison With Cardiac Magnetic Resonance and Implications for Guideline Recommendations.
JACC Cardiovasc Imaging
October 2024
Houston Methodist DeBakey Heart and Vascular Center, Houston, Texas, USA. Electronic address:
Background: Guidelines for echocardiographic evaluation of aortic regurgitation (AR) have not been validated against an independent quantitative standard.
Objectives: The aim of this study was to evaluate the accuracy of the ASE (American Society of Echocardiography) AR guidelines against cardiac magnetic resonance (CMR) and to develop simplified approaches for detection of significant AR.
Methods: Patients with AR underwent echocardiography and CMR <4 hours apart.
Challenges and Opportunities in Disease Surveillance and Cardiovascular Epidemiology for the Centennial Collection.
Circ Cardiovasc Qual Outcomes
October 2024
Department of Preventive Medicine, Northwestern Feinberg School of Medicine, Chicago, IL (M.C., D.M.L.-J.).
Hemodynamic Response after Intra-aortic Balloon Counter-Pulsation in Cardiac Amyloidosis and Cardiogenic Shock.
J Card Fail
October 2024
Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Kauffman Center for Heart Failure Treatment and Recovery, Cleveland Clinic, Cleveland, Ohio. Electronic address:
Article Synopsis
- In patients with heart failure-related cardiogenic shock due to cardiac amyloidosis, using an intra-aortic balloon pump (IABP) may enhance hemodynamic stability and support their transition to advanced therapies like heart transplants.
- A study reviewed 23 patients with cardiac amyloid who received IABP and found a 1-year survival rate of 74%, with 65% of them progressing to heart transplants.
- The use of IABP notably increased mean arterial pressure and cardiac indices while decreasing various pressures related to heart function, indicating significant improvement in their cardiovascular status.
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