Many children and adolescents with ADHD become adults with ADHD. The clinical picture may be modified from that seen with youth; however, the hyperactivity, inattention, and impulsivity persist. These behaviors affect the individual in his or her education, work, relationship, and home settings. If this adult had learning disabilities as a child and adolescent, they will continue into adulthood. Many of the emotional, behavioral, and social problems of the past continue as well. If the child or adolescent with ADHD is identified early and treated properly throughout the school years, fewer secondary problems are carried into adulthood. If not identified early or if treated during childhood and not during adolescence, a greater number of emotional, behavioral, and social problems can occur in the adult. Identification of ADHD in adulthood is critical. Treatment with medications and with psychosocial interventions is essential. Educational, individual, and career counseling may be of significant importance. The consequence of missing this diagnosis or of not addressing the problems often related to ADHD is a less than functional and successful adult.
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Am J Case Rep
December 2024
Department of Molecular Medicine and Surgery, Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden.
BACKGROUND Limb-girdle muscular dystrophy recessive 1 (LGMDR1) is an autosomal recessive degenerative muscle disorder characterized by progressive muscular weakness caused by pathogenic variants in the CAPN3 gene. Desmoplastic small round cell tumors (DSRCT) are ultra-rare and aggressive soft tissue sarcomas usually in the abdominal cavity, molecularly characterized by the presence of a EWSR1::WT1 fusion transcript. Mouse models of muscular dystrophy, including LGMDR1, present an increased risk of soft tissue sarcomas.
View Article and Find Full Text PDFPurpose: To examine associations between clinical measures (self-reported and clinician-administered) and subsequent injury rates in the year after concussion return to play (RTP) among adolescent athletes.
Methods: We performed a prospective, longitudinal study of adolescents ages 13-18 years. Each participant was initially assessed within 21 days of concussion and again within 5 days of receiving RTP clearance from their physician.
Behav Res Methods
December 2024
Department of Psychology, Bielefeld University, Universitätsstraße 25, 33615, Bielefeld, Germany.
Following the (revised) latent state-trait theory, the present study investigates the within-subject reliability, occasion specificity, common consistency, and construct validity of cognitive control measures in an intensive longitudinal design. These indices were calculated applying dynamic structural equation modeling while accounting for autoregressive effects and trait change. In two studies, participants completed two cognitive control tasks (Stroop and go/no-go) and answered questions about goal pursuit, self-control, executive functions, and situational aspects, multiple times per day.
View Article and Find Full Text PDFSci Rep
December 2024
Postgraduate Program in Health and Nutrition, School of Nutrition, Federal University of Ouro Preto, Ouro Preto, 35400-000, Brazil.
Atherosclerotic vascular changes can begin during childhood, providing risk for cardiovascular disease (CVD) in adulthood. Identifiable risk factors such as dyslipidemia accelerate this process for some children. The apolipoprotein B (APOB) gene could help explain the inter-individual variability in lipid levels among young individuals and identify groups that require greater attention to prevent CVD.
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December 2024
Department of Endocrinology, Children's Hospital, Zhejiang University School of Medicine, National Children's Regional Medical Center, National Clinical Research Center for Child Health, 3333 Binsheng Road, Hangzhou, 310052, Zhejiang Province, China.
Williams Syndrome (WS) is a rare neurodevelopmental disorder with a prevalence of 1 in 7500 to 1 in 20,000 individuals, caused by a microdeletion in chromosome 7q11.23. Despite its distinctive clinical features, the underlying metabolic alterations remain largely unexplored.
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