The present review confirms the existence of the so-called "ovarian-derived prorenin-angiotensin cascade". It also describes the physiopathology of the system and, consequently, its role in the genesis of phenomena concerning reproductive function such as ovulation, steroid synthesis and folliculogenesis. Moreover, the "ovarian-derived prorenin-angiotensin cascade" appears to play an important role in the aetiopathogenesis of diseases such as ovarian tumours, ovarian hyperstimulation syndrome and ectopic pregnancy.
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Physiopathology of the renin-angiotensin system in the ovary.
Minerva Endocrinol
June 1999
Department of Medical Physiopathology, University of Rome La Sapienza.
The present review confirms the existence of the so-called "ovarian-derived prorenin-angiotensin cascade". It also describes the physiopathology of the system and, consequently, its role in the genesis of phenomena concerning reproductive function such as ovulation, steroid synthesis and folliculogenesis. Moreover, the "ovarian-derived prorenin-angiotensin cascade" appears to play an important role in the aetiopathogenesis of diseases such as ovarian tumours, ovarian hyperstimulation syndrome and ectopic pregnancy.
View Article and Find Full Text PDFPhysiopathology of the renin-angiotensin system in the ovary.
Panminerva Med
March 1998
Department of Medical Physiopathology, University of Rome La Sapienza, Italy.
The present review confirms the existence of the so-called "ovarian-derived prorenin-angiotensin cascade". It also describes the physiopathology of the system and, consequently, its role in the genesis of phenomena concerning reproductive function such as ovulation, steroid synthesis and folliculogenesis. Moreover, the "ovarian-derived prorenin-angiotensin cascade" appears to play an important role in the aetiopathogenesis of diseases such as ovarian tumours, ovarian hyperstimulation syndrome and ectopic pregnancy.
View Article and Find Full Text PDFOvarian derived prorenin-angiotensin cascade in human reproduction.
Fertil Steril
December 1994
Division of Reproductive Endocrinology, University of Southern California School of Medicine, Los Angeles.
Objective: To review the available literature concerning the renin-angiotensin system of the human and animal ovary and to outline the clinical relevance of this system.
Design: The location, function, and regulation of the components of the ovarian prorenin cascade are described. The possible functions of this system as well as its association with common gynecologic problems are also given.
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