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Antibiotic therapy for treating overactive bladder is not supported by clinical evidence.
Nat Rev Urol
January 2025
Sheffield Teaching Hospitals, Sheffield, UK.
A number of reports have suggested that the use of prolonged antibiotic treatment could be an effective therapy for patients with overactive bladder (OAB); however, this approach is contrary to existing recommendations regarding the prolonged non-specific use of antibiotics. The existing evidence in this area seems to be circumstantial and anecdotal but, despite this limitation, the use of long-term antibiotic therapy for OAB seems to be increasing. Review and synthesis of the existing evidence for use of antibiotic therapy in patients with OAB identify few studies - just seven papers and four conference proceedings - which are heterogeneous in their design, inclusion and exclusion criteria, treatment regimen employed, approach to the use of antimuscarinic medications, follow-up protocols, and measured outcomes.
View Article and Find Full Text PDFAdvancements and future perspectives in nutrient film technique hydroponic system: a comprehensive review and bibliometric analysis.
Front Plant Sci
December 2024
Department of Soil, Plant and Food Sciences, University of Bari "Aldo Moro", Bari, Italy.
In the context of climate change, reducing the environmental impact of agriculture has become increasingly critical. To ensure sustainable food production, it is essential to adopt cultivation techniques that maximize resource efficiency, particularly in water and nutrient usage. The Nutrient Film Technique (NFT) is one such hydroponic system, designed to optimize water and nutrient use, making it a valuable tool for sustainable agriculture.
View Article and Find Full Text PDFHotspots and status of Fetal Alpha-Thalassemia from 2009 to 2023: a bibliometric analysis.
Front Pediatr
December 2024
Maternity and Child Health Care of Guangxi Zhuang Autonomous Region, Nanning, China.
Objective: to evaluate the research status and development hotspots of fetal α-thalassemia by quantitatively analyzing the diagnostic status, key areas, related management measures and prospects of the disease by bibliometrics.
Methods: The global literature on fetal α-thalassemia and severe α-thalassemia from 2009-2023 in the Web of Science Core Collection (WOSCC) was visually analyzed by VOSviewer and CiteSpace.
Results: (1) The examination of the quantity of publications concerning fetal α-thalassemia indicates a rising tendency prior to 2018, followed by a decrease after 2018.
Research on the mechanism of core acupoints in electroacupuncture for functional constipation based on data mining and network acupuncture.
Front Med (Lausanne)
December 2024
Department of Chinese Medicine, The Affiliated Taizhou's People Hospital of Nanjing Medical University, Taizhou, China.
Aim: Functional Constipation (FC) is a common gastrointestinal disorder that imposes a considerable strain on global health. It negatively impacts the quality of life and results in significant healthcare expenditures. Current treatments, such as lifestyle changes and medications, fail to meet patient satisfaction due to efficacy and safety issues.
View Article and Find Full Text PDFPhotoinduced Autopromoted Ni-Catalyzed Three-Component Arylsulfonation Inspired by Density Functional Theory/Time-Dependent Density Functional Theory-Simulated Photoactive Nickel Species.
Org Lett
December 2024
Chemical Biology Center, School of Pharmaceutical Sciences & Institute of Materia Medica, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China.
The structure of the novel photoactive nickel species was simulated by density functional theory (DFT)/time-dependent density functional theory (TD-DFT) calculations. The application of the simplified photoactive nickel catalyst was demonstrated in a photoinduced nickel-catalyzed three-component arylsulfonation of 1,6-enynes. This reaction was autopromoted and proceeded in the absence of an additional photocatalyst.
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