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On-TRACC Pilot Study: A Novel Intervention for Persistent Post-Concussive Cognitive Symptoms.

J Head Trauma Rehabil

January 2025

Author Affiliations: VA Puget Sound Health Care System, Seattle, Washington (Drs Pagulayan, Rau, and Sheppard, and Ms Onstad-Hawes, and Dr Williams); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington (Drs Pagulayan and Sheppard); and Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, Washington (Ms Shulein, and Drs Hoffman and Williams).

Objective: To present the results of a pilot study of On-TRACC (Tools for Recovery and Clinical Care), a novel intervention for individuals experiencing persistent cognitive difficulties after mild traumatic brain injury (mTBI). On-TRACC is a 5-session, 1:1 manualized treatment that integrates psychoeducation, cognitive rehabilitation strategies, and self-management skills to target symptoms and increase understanding of the interaction between cognitive difficulties, injury history, and comorbid medical and psychological conditions. The primary study goals were to evaluate the feasibility, acceptability, and preliminary effectiveness of On-TRACC.

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Article Synopsis
  • * This study aims to test the effectiveness of GAIN Lite, a new intervention combined with standard care, for adults experiencing persistent post-concussion symptoms (PPCS).
  • * GAIN Lite includes remote interviews, e-learning, and counseling from therapists, potentially providing better access to treatment and reducing chronic issues for those with transportation difficulties.
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Article Synopsis
  • - Cerebrovascular dysfunction following pediatric mild traumatic brain injury (pmTBI) is not well-studied compared to other injuries, but this study aimed to analyze cerebrovascular reactivity (CVR) and cerebral blood flow (CBF) in youths aged 8-18 post-injury.
  • - Researchers collected data approximately one week and four months after the injury, observing subtle clinical and cognitive deficits at the one-week mark that improved over time for some but not all participants.
  • - The study found increased CVR responses in pmTBI patients, particularly in certain brain regions, and noted that cerebrovascular dysfunction could persist for up to four months after the injury without a direct link to cognitive deficits or post-concussive
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Article Synopsis
  • The study aims to evaluate the safety and effectiveness of a targeted form of Transcranial Magnetic Stimulation (rTMS) in patients suffering from post-concussive syndrome (PCS) after traumatic brain injuries (TBI).
  • Researchers reviewed the experiences of 19 patients who underwent personalized rTMS treatment, identifying targets using advanced machine learning techniques to improve their quality of life and reduce symptoms.
  • Results indicated significant improvements in overall well-being and reductions in symptoms of depression and anxiety among the patients, suggesting that this method could be a promising treatment for PCS, warranting further research.
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Introduction: Early discharge from the emergency department (ED) or a 6-hour observation in the ED are two methods for management of patients with mild traumatic brain injury (mTBI) with normal brain computed tomography (CT) scan. This study aimed to compare the outcomes of the two management options.

Methods: This study is a single-center, open-label, pilot randomized case control study conducted in the ED of Ramathibodi Hospital from June 2022 to September 2023.

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