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Effects of Direct and Indirect Suggestions for Analgesia: The Role of Hypnotizability and Expectation of Pain Relief.
J Pain
December 2024
Interdepartmental Pain Center, Department of Pathophysiology and Transplants, University of Milan, Milan, Italy.
Among the methods for cognitive control of pain, the suggestions for analgesia-direct or indirect-have been widely and successfully used in experimental and clinical trials. The primary aim of this study was to contribute to the debate about the difference in the effectiveness of indirect and direct suggestions for the management of experimental pain in the ordinary state of consciousness. The secondary aim of the study was to ascertain the role of hypnotizability and expectation of pain relief in the suggestions' effect.
View Article and Find Full Text PDFEthics in hepatology: A professional and very personal journey.
Clin Liver Dis (Hoboken)
June 2024
Geisel School of Medicine at Dartmouth College/Section of Gastroenterology and Hepatology DHMC, Hanover, New Hampshire, USA.
"Pleasure to Pain?" The Impact of the COVID-19 Lockdown on Sexual Violence in Marriages: Experiences of Rural Ghanaian Women.
Violence Against Women
May 2024
Department of Sociology, The Chinese University of Hong Kong, Sha Tin, Hong Kong.
In many parts of the world, particularly in rural areas, sexual violence remains a serious issue. However, cultural orientations urge women to be submissive and obedient sexual partners in marriages. Hence, during COVID-19 lockdowns, when women were thought to be sexually assaulted most, this study used a chain referral sample technique to recruit 20 married rural Ghanaian women to examine their lived experiences of sexual violence.
View Article and Find Full Text PDFEffect of Body Mass Index on Effectiveness of CT versus Invasive Coronary Angiography in Stable Chest Pain: The DISCHARGE Trial.
Radiology
February 2024
School of Cardiovascular and Metabolic Health, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom (R.S., D.C., C.B., C.D.); Golden Jubilee National Hospital, Clydebank, United Kingdom (D.C., C.B.); Heart and Vascular Center, Semmelweis University, Budapest, Hungary (B.M., P.M.H., T. Bárány, B.S., M.V.N.); Departments of Cardiology (K.F.K., A.D.K.) and Radiology (K.F.K., A.D.K.), Copenhagen University Hospital-Rigshospitalet & Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Cardiology, Southeastern Health and Social Care Trust, Belfast, United Kingdom (P.D., C.O., S. Kelly, S.R.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (J.R.P., F.X.V., B.G.d.B.); Centro de Investigación Biomédica en Red, Madrid, Spain (J.R.P., F.X.V., B.G.d.B.); Department of Cardiology, Paul Stradins Clinical University Hospital, Riga, Latvia (A.E.); University of Latvia, Riga, Latvia (A.E.); Department of Cardiology, Motol University Hospital, Prague, Czech Republic (J.V., M.H.); Department of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania (G.Š.); Department of Cardiology, Hospital of Lithuanian University of Health Sciences, Kaunas, Lithuania (G.Š.); Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia (N.Č.A., F.A.); Department of Cardiology, Institute for Cardiovascular Diseases of Vojvodina, Novi Sad, Serbia (N.Č.A., F.A.); Department of Radiology, University of Leipzig Heart Centre, Leipzig, Germany (M.G.); Department of Radiology, St. Vincent's University Hospital, Dublin, Ireland (J.D.D.); School of Medicine, University College Dublin, Dublin, Ireland (J.D.D.); Department of Cardiology, Basurto Hospital, Bilbao, Spain (I.D., A.R.); Departments of Cardiology (G.D.) and Radiology (E.T.), Aintree University Hospital, Liverpool, United Kingdom; Edge Hill University, Ormskirk, United Kingdom (G.D.); Department of Radiology, Charité-Universitätsmedizin Berlin Campus Mitte, Charitéplatz 1, Freie Universität Berlin and Humboldt-Universität zu 10117 Berlin, Germany (E.Z., S.F., M. Mohamed, M.R., V.W., M.E., M.B., M.D.); National Institute of Cardiology, Warsaw, Poland (C. Kępka, M.K.); Department of Cardiology, Internal Medicine Clinic, Clinical Hospital Center Zemun, Belgrade, Serbia (R.V., A.Z.); Faculty of Medicine, University of Belgrade, Belgrade, Serbia (R.V.); Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Rome, Italy (M. Francone); Department of Biomedical Sciences, Humanitas University, Milan, Italy (M. Francone); Department of Cardiology, Provincial Specialist Hospital in Wroclaw, Wroclaw, Poland (M.I.S.); Department of Internal Medicine III, Department of Cardiology, Innsbruck Medical University, Innsbruck, Austria (F.P.); Turku PET Centre, Turku University Hospital and University of Turku, Turku, Finland (J.K.); Department of Cardiology, Centro Hospitalar de Vila Nova de Gaia-Espinho, Vila Nova de Gaia, Portugal (R.F., V.G.R.); Department of Cardiology, Alb Fils Kliniken, Göppingen, Germany (S.S., T.D.); Department of Radiology, University of Cagliari, Cagliari, Italy (L.S.); Department of Cardiology, Royal Liverpool University Hospital, Liverpool, United Kingdom (B.R., M. Fisher); Institute for Cardiovascular Medicine and Science, Liverpool Heart and Chest Hospital, Liverpool, United Kingdom (B.R., M. Fisher); Institute of Public Health, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Germany (N.R.); ECRIN-ERIC (European Clinical Research Infrastructure Network-European Research Infrastructure Consortium), Paris, France (C. Kubiak); Department of Public Health, Section for Health Services Research, University of Copenhagen, Copenhagen, Denmark (K.S.H.); Bavarian Cancer Registry, Bavarian Health and Food Safety Authority, Munich, Germany (J.M.N.); Department of Radiology, Medical Imaging Center, Semmelweis University, Budapest, Hungary (P.M.H.); Center of Advanced Research in Multimodality Cardiac Imaging, CardioMed Medical Center, Targu Mures, Romania (I.B., I.R.); Department of Radiology, Paul Stradins Clinical University Hospital, Riga, Latvia (L.Z.); Institute of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania (A.J.); Department of Radiology, Kaunas Clinics, Kaunas, Lithuania (A.J.); Department of Cardiology, University of Leipzig Heart Centre, Leipzig, Germany (M.W.); Department of Cardiology, St. Vincent's University Hospital, University College Dublin, Dublin, Ireland (S. Keane); Department of Radiology, Basurto Hospital, Bilbao, Spain (I.L.); Department of Cardiology and Angiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Germany (M.L., H.D.); Department of Clinical Internal, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (M. Mancone); Department of Radiology, Provincial Specialist Hospital in Wroclaw, Wroclaw, Poland (D.K.); Department of Radiology, Innsbruck Medical University, Innsbruck, Austria (G.F.); Heart Center, Turku University Hospital and University of Turku, Turku, Finland (M. Pietilä); Administrative Centre, Health Care District of Southwestern Finland, Turku, Finland (M. Pietilä); Department of Radiology, University of Cagliari, Cagliari, Italy (M. Porcu); Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom (M. Fisher); Department of Cardiology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Denmark (C.S.); Department of Cardiology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Tirgu Mures, Romania (R.A.); Section of Cardiology, Department of Medicine, Copenhagen University Hospital of Glostrup, Glostrup, Denmark (J.A.); Department of Radiology, Hospital Universitario Vall d'Hebron, Institut de Recerca, Universitat Autònoma de Barcelona, Barcelona, Spain (H.C.C.); Department of Cardiology, Nordsjaellands Hospital, Hillerod, Denmark (B.J.); Department of Internal Medicine, Clinic of Cardiology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Targu Mures, Romania (R.H., T. Benedek); DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany; Berlin Institute of Health, Berlin, Germany (H.D., M.D.); Berlin University Alliance, Berlin, Germany (M.D.); Department of Clinical Epidemiology and Applied Biostatistics, Universitätsklinikum Tübingen, Tübingen, Germany (L.M.S.H., P.M.); Institute of Biometry and Clinical Epidemiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Germany (K.N.); Oregon Health & Science University, Portland, Ore (M. Ferencik); County Clinical Emergency Hospital Targu Mures, Targu Mures, Romania (T. Benedek); Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany (M.D.); and Deutsches Herzzentrum der Charité (DHZC), Berlin, Germany (M.D.).
Background Recent trials support the role of cardiac CT in the evaluation of symptomatic patients suspected of having coronary artery disease (CAD); however, body mass index (BMI) has been reported to negatively impact CT image quality. Purpose To compare initial use of CT versus invasive coronary angiography (ICA) on clinical outcomes in patients with stable chest pain stratified by BMI category. Materials and Methods This prospective study represents a prespecified BMI subgroup analysis of the multicenter Diagnostic Imaging Strategies for Patients with Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (DISCHARGE) trial conducted between October 2015 and April 2019.
View Article and Find Full Text PDFBACKGROUND: EMBARK, a controlled trial reported elsewhere, showed enzalutamide plus leuprolide (combination) and enzalutamide monotherapy prolonged metastasis-free survival versus placebo plus leuprolide (alone) in patients with high-risk biochemically recurrent prostate cancer. Health-related quality of life was also analyzed but not reported. METHODS: In EMBARK, patients with biochemical recurrence (prostate-specific antigen doubling time of ≤9 months) were randomly assigned (1:1:1) to combination (n=355), leuprolide-alone (n=358), or enzalutamide monotherapy (n=355).
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