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Probiotic treatment induces changes in intestinal microbiota but does not alter SCFA levels in peritoneal dialysis patients-a randomized, placebo-controlled trial.
Sci Rep
December 2024
Department of Nephrology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
The gut microbiota alterations interact with the pathogenesis and progression of chronic kidney disease (CKD). Probiotics have received wide attention as a potential management in CKD. We investigated the effects of Lactobacillus paracasei N1115 (LP N1115) on intestinal microbiota and related short-chain fatty acids (SCFAs) in end stage kidney disease patients on peritoneal dialysis (PD) in a single-center, prospective, randomized, double-blind, placebo-controlled study.
View Article and Find Full Text PDFIodine starch test in a peritoneal dialysis-related hydrothorax.
Perit Dial Int
November 2024
Department of Renal Medicine, Sengkang General Hospital, Singapore.
Prevention of peritoneal adhesions after gynecological surgery: a systematic review.
Arch Gynecol Obstet
August 2024
Department of Women's Health, University Hospital Tuebingen, Tübingen, Germany.
Importance: The formation of adhesions after gynecological surgery not only has detrimental impacts on those affected, including pain, obstruction, and infertility, but also imposes a high economic burden on healthcare systems worldwide.
Objective: The aim of this review was to evaluate the adhesion prevention potential of all currently available adhesion barriers for gynecological surgery.
Evidence Acquisition: We systematically searched MEDLINE and CENTRAL databases for randomized controlled trials (RCTs) on the use of adhesion barriers as compared with peritoneal irrigation or no treatment in gynecological surgery.
Article Synopsis
- Adhesions are common complications after abdominal surgery, and numerous adhesion barriers have been developed to prevent them, but there's been no recent comprehensive review of their effectiveness.
- A systematic analysis included 20 studies with 171,792 patients, showing that most adhesion barriers provided unclear benefits, with bioresorbable types showing the most promise in colorectal surgeries.
- While some barriers can reduce complications like bowel obstructions, there are significant risks, such as abscesses and leaks, suggesting that their use should be tailored to individual cases rather than applied universally.
Comparison of adhesion prevention capabilities of the modified starch powder-based medical devices 4DryField PH, HaemoCer™ PLUS and StarSil in the Optimized Peritoneal Adhesion Model.
Int J Med Sci
January 2024
Department of General, Visceral and Transplantation Surgery, Hanover Medical School, Carl-Neuberg-Str. 1, 30625 Hanover, Germany.
Article Synopsis
- The study tested the efficacy of four starch-based hemostats (4DryField PH, Arista AH, HaemoCer PLUS, and StarSil) for preventing peritoneal adhesion formation in a rat model.
- 4DryField PH was the only product that significantly reduced adhesion formation, while HaemoCer PLUS and StarSil showed no statistically significant effect.
- The findings suggest that not all starch-based hemostats are effective for adhesion prevention, casting doubt on their general capability in this regard.
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