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Low Rate of Bacterial Coinfections and Antibiotic Overprescribing During COVID-19 Pandemic: A Retrospective Study from Oman.
Oman Med J
July 2023
Infection Diseases Unit, Department of Medicine, Royal Hospital, Muscat, Oman.
Objectives: The recommended treatment for COVID-19 includes antiviral drugs, corticosteroids, immunomodulatory drugs, low molecular weight heparin, as well as antibiotics. Although COVID-19 is a viral disease, many studies indicate that antibiotics are prescribed frequently, mainly to treat suspected bacterial coinfection. At the same time, the prevalence of bacterial coinfections during COVID-19 is rather low indicating the significant antibiotic overuse in these patients.
View Article and Find Full Text PDFProphylactic or therapeutic doses of heparins for COVID-19 infection? A retrospective study.
Aging Clin Exp Res
January 2021
Primary Care Department, Azienda ULSS 3 [Unità Locale Socio Sanitaria] "Serenissima", Dolo-Mirano District, Via Murano, 17 Spinea, Venice, Italy.
Background: Coronavirus disease 19 (COVID-19) is a global outbreak. COVID-19 patients seem to have relevant coagulative abnormalities, even if they are not typical of disseminated intravascular coagulopathy (DIC) of the kind seen in septicaemia. Therefore, anticoagulant therapy with heparins is increasing in interest for a clinical approach to these patients, particularly if older.
View Article and Find Full Text PDFAssessment of the adherence to and costs of the prophylaxis protocol for venous thromboembolism.
Clinics (Sao Paulo)
March 2020
Departamento de Farmacos e Medicamentos, Faculdade de Ciencias Farmaceuticas, Universidade Estadual de Sao Paulo (UNESP), Araraquara, SP, BR.
Objectives: Evaluate adherence to the therapeutic prophylaxis protocol for venous thromboembolism (VTE) as well as the costs of this practice.
Methods: A descriptive and cross-sectional study was conducted at a State General Hospital in Brazil through reports of drug dispensions, prescriptions and risk stratification of patients. Adherence to the VTE prophylaxis protocol was monitored.
Immune modulation treatments-where is the evidence?
Fertil Steril
June 2017
Department of Obstetrics and Gynecology, Zealand University Hospital, Roskilde, Denmark; Department of Obstetrics and Gynaecology, University of Southampton, Princess Anne Hospital, Southampton, United Kingdom. Electronic address:
While advances in assisted reproductive techniques have been substantial, failure of the apparently viable embryo to implant remains a source of distress and frustration to patients and specialists alike. The unique maternal immunological response to the embryo and the notion that defects in early placentation underlie the great complications of pregnancy have focused attention on the therapeutic potential of peri-implantation immunomodulation. On the face of it, the rationale for this approach is very attractive.
View Article and Find Full Text PDFPlatelet Transfusions in Pediatric Intensive Care.
Pediatr Crit Care Med
September 2016
1Division of Pediatric Critical Care Medicine, Department of Pediatrics, Sainte-Justine Hospital, Université de Montréal, Montréal, QC, Canada. 2Division of Hematology-Oncology, Department of Pediatrics, Sainte-Justine Hospital, Université de Montréal, Montréal, QC, Canada. 3Research Center, Sainte-Justine Hospital, Université de Montréal, Montréal, QC, Canada.
Objectives: To characterize the determinants of platelet transfusion in a PICU and determine whether there exists an association between platelet transfusion and adverse outcomes.
Design: Prospective observational single center study, combined with a self-administered survey.
Setting: PICU of Sainte-Justine Hospital, a university-affiliated tertiary care institution.
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