Collagenous fibroma (desmoplastic fibroblastoma) is a recently described entity in the medical literature. This entity has been reported in various locations, including the upper extremities, posterior neck, upper back, lower extremities, abdominal wall, and hip. We report an interesting case of an 88-year-old man who presented with an apparent goiter involving the right anterolateral neck. Histologic studies revealed a well-circumscribed, paucicellular lesion composed of stellate and spindle-shaped fibroblasts separated by bundles of collagen. No mitotic figures, necrosis, or calcification was observed. The stellate and spindle-shaped cells were positive for vimentin and focally positive for desmin, indicating myofibroblastic differentiation. Our case exemplifies the diagnostic difficulties that these tumors may pose from the clinical and radiologic standpoint when they clinically present as a goiter.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s1092-9134(00)90040-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
An Unusual Case of Intraosseous Desmoplastic Fibroblastoma (Collagenous Fibroma) of the Mandible.
Cureus
December 2024
Laboratory and Blood Bank, Anatomic Pathology Section, King Faisal Hospital, Makkah, SAU.
Desmoplastic fibroblastoma (collagenous fibroma) is a rare, benign fibroblastic/myofibroblastic tumor that usually arises in the subcutaneous and intramuscular tissues. This tumor type has rarely been described to arise primarily in bones. This is a case of intraosseous desmoplastic fibroblastoma occurring in the mandible of a 35-year-old woman that was detected incidentally during a routine dental examination.
View Article and Find Full Text PDFDesmoplastic (collagenous) fibroma of the parietal bone: Case report and review of the literature.
J Clin Imaging Sci
December 2024
Department of Radiology, Weifang People's Hospital, Weifang, China.
Desmoplastic fibroma (DF) is an uncommon benign bone tumor that typically affects the facial bones, with cerebral cranium involvement being extremely rare. We report a unique case of DF in the parietal bone of a 28-year-old woman, notable for its rapid growth during pregnancy-a phenomenon not previously documented. The imaging features of this case also differ from all but one previously reported case.
View Article and Find Full Text PDFA Case of Desmoplastic Fibroma of the Thoracic Spine with Incomplete Paralysis of both Lower Limbs.
Spine Surg Relat Res
November 2024
Department of Orthopaedic Surgery, Shiga University of Medical Science, Shiga, Japan.
Airway management in pediatric patients undergoing microvascular free tissue transfer reconstruction after mandibulectomy.
Int J Pediatr Otorhinolaryngol
December 2024
Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address:
Objectives: Microvascular free tissue transfer (MVFTT) for head and neck reconstruction is infrequently performed in pediatric patients. There is a paucity of data on perioperative airway management in pediatric MVFTT, such as the need for tracheostomy, which can pose higher morbidity to young patients due to potential long-term effects on the softer, more pliable laryngotracheal cartilage. Our objective was to report airway outcomes on pediatric patients undergoing MVFTT after segmental mandibulectomy with or without tracheostomy.
View Article and Find Full Text PDFDesmoplastic Fibroblastoma (Collagenous Fibroma) of the Knee: A Case Report and Literature Review.
Cancer Diagn Progn
November 2024
Section of Orthopaedic Surgery, Department of Medicine, Fukuoka Dental College, Fukuoka, Japan.
Background/aim: Desmoplastic fibroblastoma, also known as collagenous fibroma, is a rare benign mesenchymal neoplasm that primarily arises in the subcutaneous tissue of upper extremities and limb girdles. The knee is an uncommon location for desmoplastic fibroblastoma. Recent studies have demonstrated the presence of immunoreactivity for FOS like 1 (FOSL1) and rearrangements of FOSL1.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!