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Is global health truly global? A hashtag analysis of #GlobalHealth disparities on X.
Front Public Health
December 2024
Global Remote Research Scholars Program, St. Paul, MN, United States.
Background: X (Formerly known as Twitter) healthcare hashtags are a popular healthcare informatics and educational tool among medical professionals. #Globalhealth is one such widely used hashtag with extensive engagement. This study analyses #GlobalHealth to understand its pattern, global digital distribution, and other parameters during the COVID-19 pandemic on X.
View Article and Find Full Text PDFBacteria-Powered Self-Healing Concrete: Breakthroughs, Challenges, and Future Prospects.
J Ind Microbiol Biotechnol
December 2024
Botany and Microbiology Department, Faculty of Science, Tanta University, Tanta 31527, Egypt.
In a world where concrete structures face constant degradation from environmental forces, a revolutionary solution has emerged: bio-self-healing concrete. This innovation involves embedding dormant bacteria within the concrete mix, poised to spring into action when cracks form. As moisture seeps into the cracks, these bacterial agents are activated, consuming nutrients and converting them into calcium carbonate, a natural substance that fills and repairs the fractures, restoring the material's integrity.
View Article and Find Full Text PDFRapid and non-invasive renal injury diagnosis unlocked by a glimpse into urinary protein particle size and charge.
Biosens Bioelectron
March 2025
College of Pharmacy and International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education, Jinan University, Guangzhou, 510632, China. Electronic address:
Urinary protein, an important marker for early detection of kidney injury, would change in type and content dynamically with the degree of kidney injury due to the particle size and charge selectivity of the glomerular filtration system, making it significantly valuable for accurate classification and early diagnosis. In this study, we developed a fluorescence sensor (Ami-AuNP/DNAs) based on charge interaction to rapidly identify the progression of kidney injury. When the positively charged Ami-AuNP combines with negatively charged DNAs, fluorescence quenching occurs, and urine proteins that appear compete with the DNAs, leading to fluorescence recovery.
View Article and Find Full Text PDFCaloric restriction mimetics: Pinostilbene versus resveratrol regarding SIRT1 and SIRT6 interaction.
Adv Med Sci
November 2024
Department of Pharmacology, Faculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Purpose: Caloric restriction (CR), the permanent or periodic reduction of caloric intake, is a dietary strategy that promotes longevity and healthspan, yielding multiple beneficial effects, such as improved insulin sensitivity and mitochondrial function, decreased body weight, and mitigation of cardiometabolic risk factors. The purpose of our study was the in silico and in vitro assessment of the effects exerted by pinostilbene on SIRT1 and SIRT6 compared to those of resveratrol, a known activator of these enzymes.
Materials And Methods: Molecular docking was carried out to determine the interactions with SIRT1 and SIRT6 and, further, the effect of pinostilbene on their activity was tested in vitro to evaluate if it parallels resveratrol's effects regarding SIRT activation.
A Glimpse for the subsistence from pandemic SARS-CoV-2 infection.
Bioorg Chem
November 2024
School of Pharmaceuticals and Population Health Informatics, Faculty of Pharmacy, DIT University, Dehradun, Uttarakhand, 248009, India.
COVID-19 is an emerging viral pandemic caused by SARS-CoV-2, which is the causative agent of unprecedented disease-causing public health threats globally. Worldwide, this outbreak is wreaking havoc due to failure in risk assessment regarding the urgency of the pandemic. As per the reports, many secondary complications which include neurological, nephrological, gastrointestinal, cardiovascular, immune, and hepatic abnormalities, are linked with COVID -19 infection which is associated with prominent respiratory disorders including pneumonia.
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