This study was designed to investigate the effects of objective and subjective stress levels and perceived control on serum uric acid (SUA). Respondents were 2,504 male and 1,176 female manufacturing employees. Objective job-related stress was assessed by the Ergonomic Stress Level (ESL) inventory (S. Melamed, D. Yekutieli, P. Froom, E. Kristal-Boneh, & J. Ribak, 1999). As expected, ESL was positively associated with SUA, but among male respondents only. The measure of subjective stress, environmental annoyance, was negatively related with SUA for male respondents, thus not confirming the hypothesis. Perceived control was not found to have a direct effect on SUA, after controlling for the ESL measure. For male respondents only, perceived control moderated the relationship between ESL and SUA: This relationship was negative for those reporting above-average control and positive for those reporting below-average control.
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