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Maternal Chronic Physical Conditions and Alcohol and Substance Use Disorders in the Preconception and Perinatal Periods.
J Womens Health (Larchmt)
January 2025
ICES, Toronto, Canada.
Chronic physical conditions (CPC) and alcohol and substance use disorders (SUD) frequently co-occur, but this has not been examined perinatally. We explored the combined effects of CPC and prepregnancy SUD on perinatal SUD-related adverse events and outpatient care. This population-based study comprised 77,474 people with and 664,751 without CPC with a birth in Ontario, Canada, 2013-2020.
View Article and Find Full Text PDFFluid Management in Critical Care: New Insights Into Optimal Fluid Therapy.
Cureus
December 2024
Critical Care Medicine, Star Care Multispeciality Hospital, Kozhikode, IND.
Background: Fluid management is a crucial critical care component, influencing outcomes such as organ function, renal integrity, and survival in critically ill patients. Recent evidence suggests that balanced crystalloids may offer advantages over isotonic saline, particularly in reducing the risk of acute kidney injury (AKI) and other complications. This study aimed to evaluate the impact of balanced crystalloids versus isotonic saline on clinical outcomes in the intensive care unit (ICU), focusing on AKI, renal replacement therapy (RRT), and mortality.
View Article and Find Full Text PDFClosing of a Patent Tear Above the Aortic Hiatus and Type A Aortic Dissection Outcomes.
Ann Thorac Surg Short Rep
September 2023
Department of Cardiovascular Surgery, Iwate Prefectural Central Hospital, Morioka, Iwate, Japan.
Background: A strategy combining tear-oriented initial surgical procedure and subsequent thoracic endovascular aortic repair (TEVAR) can be adopted for acute type A aortic dissection (ATAAD). This study investigated this strategy's outcomes and the role of the aortic hiatus (AH).
Methods: Overall, 192 consecutive patients with ATAAD who underwent initial surgery between 2012 and 2021 were assessed in this observational retrospective study.
Amyopathic Dermatomyositis with a Rapidly Progressing Interstitial Pneumonia.
Eur J Case Rep Intern Med
November 2024
Department of Lung Diseases and Thoracic Surgery, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Background: Clinically amyopathic dermatomyositis (CADM) is a rare subtype of idiopathic inflammatory myositis often linked with the presence of autoantibodies targeting melanoma differentiation-associated protein 5 (MDA5). Patients with CADM are at increased risk of developing rapidly progressing interstitial lung disease, which significantly increases both morbidity and mortality compared to other forms of inflammatory myopathies. While there is no standardized treatment regimen, current therapeutic strategies are generally focused on combination immunosuppressive therapies.
View Article and Find Full Text PDFAnthropogenically induced climate change has significantly increased the frequency of acute weather events, such as drought. As human activities amplify environmental stresses, animals may be forced to prioritize survival over behaviors less crucial to immediate fitness, such as socializing. Yet, social bonds may also enable individuals to weather the deleterious effects of environmental conditions.
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