An evaluation of automated low-speed handpiece preparation of canals was made by a silicone injection technique. These preparations were compared and rated with canals prepared by conventional hand instrumentation. Canals were graded on the criteria of shape, smoothness, elimation of morphologic aberrations, and apical preparations. Conventional hand istrumentation proved to be superior and required approximately the same amount of time as automated ins-rumentation in this vitro study.
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Cureus
December 2024
Department of Teaching and Research, The Second People's Hospital of Wuhu, Wuhu Hospital Affiliated to East China Normal University, Wuhu, CHN.
This narrative review assesses the effectiveness of hand gesture analogy teaching in clinical medical education, addressing the growing demand for innovative pedagogical strategies. Through a comprehensive analysis of existing literature, it evaluates the theoretical foundations, implementation strategies, and practical applications of this method across various domains of medical education. Hand gesture analogy teaching significantly enhances student learning by improving engagement, spatial reasoning, and procedural knowledge retention more effectively than conventional instructional methods.
View Article and Find Full Text PDFFront Psychol
January 2025
Department of Psychology, Friedrich-Schiller-Universität, Jena, Germany.
This research examines the factor structure and psychometric properties of two well-known Dark Triad personality trait questionnaires: the Short Dark Triad (SD3) and the Dirty Dozen (DD). By analyzing data from 11 (SD3) and 5 (DD) carefully selected studies in the United States and Canada, this meta-analysis uncovers unexpected correlations among questionnaire items, challenging existing assumptions. The study employs a two-stage structural equation modeling approach to evaluate various measurement models.
View Article and Find Full Text PDFPharmacol Res
January 2025
Medical Research Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, 510080, China. Electronic address:
T-cell lymphomas (TCLs) are heterogeneous malignancies with limited treatment options and poor outcomes. The efficacy of traditional T-cell therapies, including chimeric antigen receptor (CAR) T cells, is often constrained by immunosuppressive factors and the tumor microenvironment. On the other hand, although direct Granzyme B (GrB) administration can effectively induce tumor cell apoptosis, it lacks universal tumor targeting and efficient cellular entry mechanisms.
View Article and Find Full Text PDFJ Med Internet Res
January 2025
School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Background: Lifestyle interventions have been acknowledged as effective strategies for preventing type 2 diabetes mellitus (T2DM). However, the accessibility of conventional face-to-face interventions is often limited. Digital health intervention has been suggested as a potential solution to overcome the limitation.
View Article and Find Full Text PDFArq Bras Oftalmol
January 2025
Department of Ophthalmology and Visual Sciences, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Purpose: This study aimed to report the use, efficacy, and safety of intracameral voriconazole as an adjuvant treatment for deep fungal keratitis.
Methods: This was a prospective case series of seven eyes with fungal keratitis with anterior chamber involvement or a corneal ulcer refractory to conventional topical treatment. In addition to topical treatment with 0.
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