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Epidemiology, Clinical Characteristics and Treatment Outcomes of Infection at a Regional Hospital in Thailand.

Infect Drug Resist

January 2025

Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Objective: This retrospective cohort study evaluated the treatment outcome of infection.

Methods: In this retrospective cohort study, 476 patients with () infection who were admitted to the internal medicine ward at Lampang Hospital, Lampang, Thailand, from 1 January 2020 to 31 December 2020 were enrolled. Medical records were reviewed.

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Aims And Background: Carbapenem-resistant (CRAb), a major public health threat, causes severe infections in Intensive Care Unit (ICU) patients. It resists β-lactam antibiotics through mechanisms like New Delhi metallo-beta-lactamase (NDM).

Materials And Methods: In ICU patients, 69 species were isolated from 86 non-fermenting Gram-negative bacilli.

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Introduction: Cefiderocol is a parenteral catechol-type siderophore cephalosporin, which has been approved for the treatment of gram-negative bacterial infections. Its activity among the carbapenem-resistant gram negative bacilli (CR-GNBs) in India is largely unknown.

Methodology: We tested in-vitro susceptibility of cefiderocol in 84 CR-GNB [ carbapenem-resistant Acinetobacter baumannii (CRAB), carbapenem-resistant Pseudomonas aeruginosa (CRPA) , carbapenem-resistant Escherichia coli (CREC) and carbapenem-resistant Klebsiella pneumoniae (CRKP)] by broth microdilution(BMD) and disc diffusion (DD) using Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) breakpoints and concordance of DD was compared with BMD.

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Whole genome sequencing revealed high occurrence of antimicrobial resistance genes in bacteria isolated from poultry manure.

Int J Antimicrob Agents

January 2025

Department of Botany, Institute of Science, Banaras Hindu, University, Varanasi, Uttar Pradesh, 221005, India. Electronic address:

Global demand for food has driven expansion and intensification of livestock production, particularly in developing nations where antibiotic use is often routine. Waste from poultry production, including manure, is commonly utilized as fertilizers in agroecosystems, risking environmental contamination with potentially zoonotic bacteria and antimicrobial resistance genes (ARGs). Here, 33 bacterial isolates were recovered from broiler (n=17) and layer (n=16) chicken manure by aerobic culture using Luria Bertani agar.

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