Objectives: Sudomotor efferent nerve fiber function was studied in carpal tunnel syndrome (CTS).
Methods: Bilateral median and ulnar sympathetic skin response (SSR) were recorded by sternal stimulation in 22 bilateral and 9 unilateral patients and compared with 21 healthy volunteers.
Results: There was no significant difference between median and ulnar nerve SSR latency, amplitude or area. The median nerve SSR was not different from that of the controls. The median-to-ulnar ratios of SSR parameters were not different in patients and controls. However, the median-to-ulnar ratios of SSR amplitude and area were lower than normal in 3 out of 7 patients with normal nerve conduction whereas this abnormality was found in only 4 out of 46 patients with abnormal nerve conduction.
Conclusions: Normal SSR results, even in patients with complaints related to sudomotor sympathetic dysfunction, indicate that the SSR does not seem to be a sensitive diagnostic method in CTS.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s1388-2457(00)00333-3 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The case of a woman with bilateral Dupuytren's contractures who developed CRPS-1 after fasciectomy with no relapse on subsequent collagenase clostridium histolyticum injection and manipulation of the other hand: Considerations for implementing a Budapest criteria checklist and assessing vasomotor instability by measuring differences in skin temperature.
J Hand Ther
January 2025
Saint Joseph, MI, USA. Electronic address:
Background: For patients who experience atypical neurogenic pain thought to be complex regional pain syndrome (CRPS) after Dupuytren's fasciectomy early recognition has been reported to improve outcomes. Furthermore, given the progressive nature of Dupuytren's, individuals with a history of CRPS have been "at risk" for further surgical intervention.
Purpose: To familiarize therapists with a Budapest criteria (BC) checklist for early diagnosis of CRPS, describe how tracking sudomotor/vasomotor signs alongside differences in skin temperature were used to monitor vasomotor instability and intervention effectiveness for a patient with atypical pain after fasciectomy and to detail management of the same patient with a CRPS history who had collagenase clostridium histolyticum (CCH) injection of her other hand without exacerbating CRPS.
Association between skin sympathetic nerve activity and electrocardiogram alterations after subarachnoid hemorrhage.
Physiol Rep
January 2025
Department of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Ishikawa, Japan.
While autonomic dysregulation and repolarization abnormalities are observed in subarachnoid hemorrhage (SAH), their relationship remains unclear. We aimed to measure skin sympathetic nerve activity (SKNA), a novel method to estimate stellate ganglion nerve activity, and investigate its association with electrocardiogram (ECG) alterations after SAH. We recorded a total of 179 SKNA data from SAH patients at three distinct phases and compared them with 20 data from controls.
View Article and Find Full Text PDFPathophysiological Significance of α-Synuclein in Sympathetic Nerves: In Vivo Observations.
Neurology
February 2025
From the Autonomic Medicine Section, Clinical Neurosciences Program, Division of Intramural Research, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
Background And Objectives: Lewy body diseases (LBDs) such as Parkinson disease (PD) feature increased deposition of α-synuclein (α-syn) in cutaneous sympathetic noradrenergic nerves. The pathophysiologic significance of sympathetic intraneuronal α-syn is unclear. We reviewed data about immunoreactive α-syn, tyrosine hydroxylase (TH, a marker of catecholaminergic fibers), and the sympathetic neurotransmitter norepinephrine (NE) in skin biopsies from control participants and patients with PD, the related LBD pure autonomic failure (PAF), the non-LBD synucleinopathy multiple system atrophy (MSA), or neurologic postacute sequelae of severe acute respiratory syndrome coronavirus 2 (neuro-PASC).
View Article and Find Full Text PDFUVB Induces Sympathetic Nervous System Activation and Norepinephrine Secretion to Regulate The Skin Color of Mice Through the β2-AR/AP-1 Pathway in Epidermal Keratinocytes.
Inflammation
January 2025
Department of Dermatology, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde), NO. 1 Jiazi Road, Lunjiao, Shunde District, Foshan City, 528308, Guangdong, China.
The aim of this study was to investigate how ultraviolet B (UVB) light regulates AP-1 expression via the β2-adrenergic receptor (β2-AR) in epidermal keratinocytes, which in turn regulates melanin synthesis in melanocytes, thereby modulating downstream melanin production in skin hair follicles and altering mouse skin color. We established a UV-irradiated mouse model to investigate the effects of UV radiation on changes in skin color. By measuring changes in the expression of genes related to cutaneous sympathetic nerves, norepinephrine synthesis and melanin synthesis, we investigated the relationship between β2-AR expression and cutaneous melanogenesis and determined the localization of β2-AR in cells.
View Article and Find Full Text PDFPurpose: The aim of the current study was to evaluate changes in choroidal circulation hemodynamics after periocular skin warming at 40°C using laser speckle flowgraphy (LSFG).
Methods: Twenty-four right eyes of 24 healthy participants were included. Changes in choroidal circulation hemodynamics were determined using LSFG to evaluate the mean blur rate (MBR) of the macula, which represents choroidal blood flow velocity.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!