[Enzyme clearance in intermittent hemofiltration in patients with acute renal failure].

Aim: To characterize elimination of some enzymes in intermittent hemofiltration (HF) in patients with acute renal failure (ARF).

Material And Methods: 22 patients with oliguric ARF have undergone 52 procedures of intermittent HF. Before the procedure and after it the activity of enzymes (AA, AP, ACE, LAP, GGT, GDG, AlAT, AsAT, CPG, LDG) was measured in the samples of plasma and filtrate.

Results: Besides ACE and AlAT, all the enzymes concentrations were elevated in all the patients. HF did not change significantly the enzymes activity. Most of the enzymes were eliminated from the blood. In some samples the enzymes activity was low or absent.

Conclusion: Further studies are necessary to answer questions aroused by the findings.