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Microbial Primer: Microbiome and thermal tolerance - a new frontier in climate resilience?
Microbiology (Reading)
January 2025
Department of Zoology, University of British Columbia, Vancouver, Canada.
Microbiome-animal host symbioses are ubiquitous in nature. Animal-associated microbiomes can play a crucial role in host physiology, health and resilience to environmental stressors. As climate change drives rising global temperatures and increases the frequency of thermal extremes, microbiomes are emerging as a new frontier in buffering vulnerable animals against temperature fluctuations.
View Article and Find Full Text PDF[Treatment algorithm following first-line therapy failure in metastatic prostate cancer].
Urologie
January 2025
Klinik für Urologie, Campus Lübeck, Universitätsklinikum Schleswig-Holstein, Lübeck, Deutschland.
This article provides a comprehensive overview of the current treatment options for patients with metastatic castration-resistant prostate cancer (mCRPC) following the failure of first-line therapy. Although significant progress has been made in the primary treatment of hormone-sensitive prostate cancer, the management of mCRPC remains a clinical challenge. The article outlines the diagnostic criteria for mCRPC, which can be confirmed through biochemical progression and imaging techniques.
View Article and Find Full Text PDFTheory-driven assessment of cognitive flexibility in bulimia nervosa: a preliminary study.
Cogn Neuropsychiatry
January 2025
Department of Psychology, Ariel University, Ariel, Israel.
Background: Cognitive flexibility (CF) is defined as the ability to switch efficiently between different concepts or tasks. Empirical evidence of CF in individuals with bulimia nervosa (BN), offers conflicting conclusions, attributed to how CF is conceptualized and operationalized. The aims of the current study were to compare CF performance of women with BN to healthy controls, utilising a CF model that includes three subtypes termed: task switching, switching sets and stimulus-response mapping.
View Article and Find Full Text PDFEducation Research: Use by Neurologists of Microteaching and Microassessment Programs for Teaching, Learning, and Patient Care Needs: A Qualitative Study.
Neurol Educ
December 2024
From the Warren Alpert Medical School of Brown University (K.A.S.), Providence, RI; Memorial Sloan Kettering Cancer Center (A.M.M.), New York, NY; Department of Neurology (J.J.M.), Yale School of Medicine, New Haven, CT; Wake Forest University School of Medicine (K.W., S.-E.G., R.E.S.), Winston-Salem, NC; American Academy of Neurology (X.S., L.S., R.R., M.M., T.D.), Minneapolis, MN; and University of Michigan School of Medicine (Z.L.), Ann Arbor, MI.
Background And Objectives: Microlearning is the acquisition of knowledge or skills in small units, commonly delivered by digital technology. NeuroBytes (NB) and Question of the Day (QOD) are 2 microinstructional programs in neurology. NB programs are brief, video-based mini-courses on clinical topics (microteaching); QODs are daily multiple-choice questions (microassessment).
View Article and Find Full Text PDFMapping the evidence of self-compassion in caregiver wellbeing for caregivers of persons with neurodegenerative disease: A scoping review.
Palliat Support Care
January 2025
Section of Geriatrics, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Objectives: Caregivers of those with neurodegenerative disease (ND) manage complex symptoms which impact their wellbeing. Self-compassion can promote maintenance of wellbeing during challenging experiences, including caregiving. Little guidance exists for observationally studying self-compassion or targeted interventions for this population.
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