Unlabelled: Knowledge of modern molecular biology is leading to the idea that aging and diseases of the aged are two different entities. Healthy life is relatively limited by the specific number of chronic conditions which are present more in old age. Up to now the idea of aging as a process in relation to the individual, organ, tissue, cell or a molecule. There are only few studies on the influence of aging within a single family and even less of aging within several generations of the same family. Genealogic level is one way of getting into the process of family system and aging throughout time. The aim of the study was to determine the significance of genealogical burden with regard to the health status in examinees with different cognitive capabilities. The difference according to sex and age was not significant between the two groups. Health status of the examinees proband in both groups showed 34.4% healthy examinees in the group D and 65.3% in group G. The difference between the two groups was statistically significant. The difference of health status of parents (II. generation) was statistically significant in both groups. Morbidity of diseases was not statistically significant. Most of the ancestors from the grandmothers and grandfathers (III generation) died. (group G--97.5%, group D--100%). Statistically significant difference is present among the diseases of the circulatory system and those of digestive system in this generation. Data on the ancestors of the IV. generation showed that all the relatives died in both groups.
Conclusion: The health status of the examinees with higher impairment in the test of cognitive capabilities is worse and they come from the families with worse health status.
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Arch Gerontol Geriatr
January 2025
Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, 12 Science Drive 2, Singapore 117549, Singapore. Electronic address:
Background: Both air pollution and low socioeconomic status (SES) are associated with worse cognitive function. The extent to which low SES may compound the adverse effect of air pollution on cognitive function remains unclear.
Methods: 7,087 older adults aged 65 and above were included from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) and followed up in 4 waves during 2008-2018.
JACC Adv
January 2025
Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia, USA. Electronic address:
Background: HIV induced endothelial dysfunction (ED) contributes to cardiovascular disease (CVD) in women with HIV (WWH). Although psychosocial stress has been implicated in the development of CVD in HIV, its impact on ED in WWH remains unknown.
Objectives: The authors hypothesized that posttraumatic stress disorder (PTSD) and HIV interact to contribute to ED in WWH.
JMIR Diabetes
January 2025
Research Institute, BC Children's Hospital, Vancouver, BC, Canada.
Background: Beyond physical health, managing type 1 diabetes (T1D) also encompasses a psychological component, including diabetes distress, that is, the worries, fears, and frustrations associated with meeting self-care demands over the lifetime. While digital health solutions have been increasingly used to address emotional health in diabetes, these technologies may not uniformly meet the unique concerns and technological savvy across all age groups.
Objective: This study aimed to explore the mental health needs of adolescents with T1D, determine their preferred modalities for app-based mental health support, and identify desirable design features for peer-delivered mental health support modeled on an app designed for adults with T1D.
JMIR Form Res
January 2025
Smith School of Business, Queen's University, Kingston, ON, Canada.
Background: Depression significantly impacts an individual's thoughts, emotions, behaviors, and moods; this prevalent mental health condition affects millions globally. Traditional approaches to detecting and treating depression rely on questionnaires and personal interviews, which can be time consuming and potentially inefficient. As social media has permanently shifted the pattern of our daily communications, social media postings can offer new perspectives in understanding mental illness in individuals because they provide an unbiased exploration of their language use and behavioral patterns.
View Article and Find Full Text PDFJ Med Internet Res
January 2025
Division of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan.
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