Some studies have suggested that noradrenergic activity may decrease with age in depressed patients. Pupil size is regulated by a balance between norepinephrine and acetylcholine. The present study compares pupil size in 10 unmedicated patients with unipolar depression (296. 3) and in 16 normal controls. Pupil size after dilation with tropicamide, a cholinergic antagonist, was inversely related to age in the patients (r=-0.87), but did not diminish with age in controls. The results suggest that pupil size may provide an index of diminished noradrenergic function with age in patients with major depression.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0165-1781(00)00155-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Pupillary dynamics in diabetic and nondiabetic patients following uneventful phacoemulsification.
Clin Exp Optom
January 2025
Department of Ophthalmology, Gaziantep City Hospital, Gaziantep, Turkey.
Clinical Relevance: Although laser refractive surgeries and multifocal intraocular lens implantation are generally avoided in patients with diabetic retinopathy, a substantial proportion of well-glycaemic-controlled type 2 diabetes mellitus patients are considered for these procedures. Pupil dynamics play a significant role in determining postoperative satisfaction in these patients.
Background: To evaluate pupillary dynamics in patients with and without diabetes following uneventful phacoemulsification surgery.
Improvement of Presbyopia, Dry Eye, Intraocular Pressure, and Near Vision Through Cassiae Tea Consumption.
Medicina (Kaunas)
December 2024
Department of Pharmacy, Tajen University, Pingtung 907, Taiwan.
: This study aimed to illustrate a novel method for improving presbyopia by drinking cassiae tea. : A total of 425 eyes from 425 participants (aged 52.5 ± 9.
View Article and Find Full Text PDFBeam Tilt Aberration Detection of the Seven-Unit Phased Fiber Laser Array.
Micromachines (Basel)
December 2024
School of Optoelectronic Engineering, Changchun University of Science and Technology, Changchun 130022, China.
In this paper, we present a method based on the conjugate image principle and micro-nano optics to detect tilt aberrations of a phased fiber laser array system. A co-aperture optics system was adapted to detect the tilt aberrations of a seven-element phased fiber laser array system simultaneously. A Kepler telescope was designed to construct the conjugate relation between the exit pupil of a fiber optic laser array system and a microlens array and also to match the size of the seven beams and the microlens array.
View Article and Find Full Text PDFIntroduction: Glaucoma is a leading cause of blindness, often progressing asymptomatically until significant vision loss occurs. Early detection is crucial for preventing irreversible damage. The pupillary light reflex (PLR) has proven useful in glaucoma diagnosis, and mobile technologies like the AI-based smartphone pupillometer (AI Pupillometer) offer a promising solution for accessible screening.
View Article and Find Full Text PDFPost-craniectomy hydrocephalus in adult traumatic brain injury patients: a systematic review and meta-analysis of risk factors and outcome.
Neurosurg Rev
January 2025
Department of Neurosurgery, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Traumatic Brain Injury (TBI) is a major cause of death, disability, and healthcare expenses worldwide. Decompressive craniectomy (DC) is a critical surgery used when there is uncontrollable swelling in the brain following a TBI. Research has shown that 27.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!