Abnormalities were studied of lipid metabolism in patients with glomerulonephritis (GN) depending on the presence of herpes infection (antibodies to herpes simplex virus and cytomegalovirus) versus similar indices in GN patients free from this infection (n = 75). Of these, 34 presented with the urinary syndrome (US), 41 had nephrotic syndrome (NS). Abnormalities of lipid metabolism in GN patients (irrespective of the syndrome) were shown to be more manifest in the presence of herpes infection. GN severity (in comparative evaluation within one entity) was not found to be dependent on the viral infection but disturbances in functional indices for the liver in patients in its presence occurred far more frequently. More profound abnormalities of lipid metabolism in GN patients in the presence of herpes virus infection can be a factor in GN chronization, affect the rate of progression of not only atherosclerotic lesions of kidneys but of glomerulosclerosis as well.
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