[[Computed imaging analysis of neutrophils: myeloperoxidase]lysis of].

Computer analysis of the cell image showed granular and diffuse activities of myeloperoxidase (MP) in the neutrophil cytoplasm. MP in the intergranular cytoplasm can be regarded as a product of secretory activity of azurophilic granules. The patterns of MP distribution in the neutrophils of normal subjects and patients with peritonitis are different. Parameters characterizing the number of MP granules in a cell, total area of granules and the zone of diffuse granular distribution of MP in combination with their optic density reflect the functional activity of neutrophils and can be used as diagnostic signs.