AI Article Synopsis

Article Abstract

We studied and quantified the effect of cyclosporine A on hepatic F-actin on bile canalicular and basolateral membranes in rats fed either soybean lecithin, triacylglycerol-enriched diet, or low-fat diet by means of confocal laser scanning microscopy imaging. The phalloidin-FITC staining of F-actin was quite normal in the lecithin-cyclosporine A group but decreased significantly in the other cyclosporine A-treated groups (by 40% and 25% of control in triacylglycerol-cyclosporine A and cyclosporine A groups, respectively). The alteration of F-actin by cyclosporine A, related to cholestasis evidenced by a decrease in bile salt secretion, was prevented by dietary soybean lecithin and amplified by dietary soybean triacylglycerol.

Download full-text PDF

Source
http://dx.doi.org/10.1023/a:1005533531756DOI Listing

Publication Analysis

Top Keywords

soybean lecithin
12
hepatic f-actin
8
cyclosporine a-treated
8
confocal laser
8
laser scanning
8
scanning microscopy
8
dietary soybean
8
cyclosporine
5
dietary lipid
4
soybean
4

Similar Publications

Mild cognitive impairment is a diagnostic category marked by declines in memory and cognitive function that are less severe than those observed in Alzheimer's disease. Previous studies have indicated that individuals with mild cognitive impairment have an elevated risk of progressing to Alzheimer's disease. The hippocampus is well known to play pivotal roles in memory and cognitive functions.

View Article and Find Full Text PDF

Optimization of Cholesterol-Loaded Cyclodextrin Combined with Soybean Lecithin as a Cryoprotectant for Rooster Sperm.

Vet Sci

December 2024

Shanghai Municipal Key Laboratory of Agri-Genetics and Breeding, Institute of Animal Husbandry and Veterinary Science, Shanghai Academy of Agricultural Sciences, Shanghai 201106, China.

There are many applications of soybean lecithin (SL) and cholesterol-loaded cyclodextrin (CLC) in sperm freezing processes. To the best of our knowledge, there have been few cases of the combined use of SL and CLC in freezing rooster semen. We investigated the effects of CLC, SL, and their combination on rooster sperm cryodamage.

View Article and Find Full Text PDF

Molecular Selectivity of a pH-Tunable Lecithin-Modified Zirconia Stationary Phase.

ACS Omega

November 2024

Graduate School of Science and Technology, Kochi University, 2-5-1 Akebono, Kochi 780-8520, Japan.

We synthesized lecithin-modified zirconia (LMZ) as an adsorbent, solid-phase extractant, and stationary phase for organic compounds such as organic acids or amino acids. The molecular selectivity of LMZ was evaluated through high-performance liquid chromatography (HPLC). LMZ exhibits electrostatic and hydrophobic interactions with organic compounds that depend on the pH of the mobile phase.

View Article and Find Full Text PDF

A growing body of evidence suggests that protein structure can be uniquely altered by lipids. However, the role of lecithin on the digestibility and immunoreactivity of allergenic protein remains poorly understood. Therefore, we investigated the impact of different protein/lecithin (P:L) ratios (5:1, 10:1, 20:1, 30:1 and 40:1) on the digestion properties, peptide profiles and immunoreactivity of β-conglycinin in vitro simulated gastrointestinal digestion.

View Article and Find Full Text PDF

This research explored the development of composite systems using konjac gum (KGM) and soy lecithin at concentrations of 1% KGM-0.01% lecithin and 1% KGM-0.2% lecithin.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!