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Is trophoblastic thickness at the embryonic implantation site a new sign of negative evolution in first trimester pregnancy? | LitMetric

AI Article Synopsis

  • - The study introduces trophoblastic thickness at the embryonic implantation site as a new indicator for monitoring pregnancy progression.
  • - Conducted from January 1998 to February 1999, it involved 592 normal pregnancies and utilized serial ultrasounds from weeks 5 to 12.
  • - Findings show that a trophoblastic thickness of ≥3 mm correlates with high sensitivity (82%) and specificity (93%) for predicting pregnancy outcomes, specifically spontaneous abortion.

Article Abstract

In this study a new sign to evaluate the evolution of pregnancy is described: the trophoblastic thickness at the embryonic implantation site. A prospective, observational study of 592 normal pregnancies with no known risk factors was carried out from January 1998 to February 1999. Serial ultrasound scans were performed from week 5 to week 12 of pregnancy. Trophoblastic thickness was measured at the embryonic implantation site to determine the significance of a difference in gestational age in weeks and a trophoblastic thickness of >/=3 mm in predicting poor prognosis in pregnancy outcome. The sensitivity of this sign in the prediction of spontaneous abortion was 82%, the specificity was 93%, the positive predictive value was 63% and the negative predictive value was 97%.

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Source
http://dx.doi.org/10.1093/humrep/15.7.1629DOI Listing

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