In chemical shift resolved spectroscopic imaging (CSI) temporal changes in the static magnetic field (drift) can lead to distortions of the phase encoding process. This can result in localization artifacts. The extent of the artifact depends on the size of the drift, the number of acquisitions, as well as on the combination of the size of the field of view and the number of phase encoding gradient steps. Furthermore, it is affected by the succession of the phase encoding gradients. Precautions are described which allow substantial minimization of the artifact.
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Hum Vaccin Immunother
December 2025
Jiangsu Provincial Medical Innovation Center, National Health Commission Key Laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Disease Control and Prevention (Jiangsu Provincial Academy of Preventive Medicine), Nanjing, China.
INO-4800 represents a DNA-based vaccine encoding the spike protein of SARS-CoV-2. This phase 2 trial evaluated the immunogenicity and safety of INO-4800 as a primary vaccination series in adults. We conducted a randomized, observer-blind, placebo-controlled phase 2 trial of intradermal injection of INO-4800 in both healthy adults and elderly individuals.
View Article and Find Full Text PDFMagn Reson Imaging
January 2025
Institute of Fluid Mechanics, University of Rostock, Rostock, Germany.
Purpose: To improve the current method for MRI turbulence quantification which is the intravoxel phase dispersion (IVPD) method. Turbulence is commonly characterized by the Reynolds stress tensor (RST) which describes the velocity covariance matrix. A major source for systematic errors in MRI is the sequence's sensitivity to the variance of the derivatives of velocity, such as the acceleration variance, which can lead to a substantial measurement bias.
View Article and Find Full Text PDFPharmaceuticals (Basel)
January 2025
School of Pharmacy, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.
infections continue to pose a significant global health challenge, particularly due to the rise of multidrug-resistant strains, random mycobacterial mutations, and the complications associated with short-term antibiotic regimens. Currently, five approved drugs target cell wall biosynthesis in . This review provides a comprehensive analysis of these drugs and their molecular mechanisms.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Haute Ecole de Gestion Genève, HES-SO, 1227 Carouge, Switzerland.
Accurate localization is crucial for numerous applications. While several methods exist for outdoor localization, typically relying on GPS signals, these approaches become unreliable in environments subject to a weak GPS signal or GPS outage. Many researchers have attempted to address this limitation, primarily focusing on real-time solutions.
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January 2025
Departamento de Ingeniería Electrónica, Universidad de Sevilla, 41092 Seville, Spain.
Variable-speed electrical drive control typically relies upon a two-loop scheme, one for torque/speed and another for stator current control. In modern drive control methods, the actual mechanical speed is needed for both loops. In practical applications, the speed is often acquired by incremental rotary encoders.
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