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Re-cherchez la Femme: A Second Look at Women in Gastroenterology in Canada.
J Can Assoc Gastroenterol
April 2020
Division of Gastroenterology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Cherchez la femme - impact of ocean acidification on the egg jelly coat and attractants for sperm.
J Exp Biol
July 2018
Department of Anatomy and Histology, School of Medical Sciences, and School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW 2006, Australia.
The impact of ocean acidification on marine invertebrate eggs and its consequences for sperm chemotaxis are unknown. In the sea urchins and , with small (93 µm) and large (393 µm) eggs, respectively, we documented the effect of decreased pH on the egg jelly coat, an extracellular matrix that increases target size for sperm and contains sperm-attracting molecules. In near-future conditions (pH 7.
View Article and Find Full Text PDFCherchez la femme: maternal incidental findings can explain discordant prenatal cell-free DNA sequencing results.
Genet Med
September 2018
Prenatal Genomics and Therapy Section, National Human Research Genome Institute, National Institutes of Health, Bethesda, Maryland, USA.
Circulating DNA fragments in a pregnant woman's plasma derive from three sources: placenta, maternal bone marrow, and fetus. Prenatal sequencing to noninvasively screen for fetal chromosome abnormalities is performed on this mixed sample; results can therefore reflect the maternal as well as the fetoplacental DNA. Although it is recommended that pretest counseling include the possibility of detecting maternal genomic imbalance, this seldom occurs.
View Article and Find Full Text PDF"Cherchez La Femme": Modulation of Estrogen Receptor Function With Selective Modulators: Clinical Implications in the Field of Urology.
Sex Med Rev
July 2017
Lahey Health Center, Burlington, MA, USA. Electronic address:
Introduction: Selective estrogen receptor modulators (SERMs) have been used off-label in men for more than 50 years. SERMs exert their action on the estrogen receptor agonistically or antagonistically. A fundamental knowledge of the complex molecular action and physiology of SERMs is important in understanding their use and future directions of study in men.
View Article and Find Full Text PDFThe Out of Africa hypothesis and the ancestry of recent humans: Cherchez la femme (et l'homme).
Gene
July 2016
Department of Brain Surgery, Faculty of Medicine, University of Lund, Sweden. Electronic address:
The Out of Africa hypothesis (OOAH) has been a mainstay in the discussion of human evolution since its presentation in the 1980's. However, recent advances in palaeontology and molecular genetics have made it possible to examine the hypothesis in a manner that was inconceivable at the time of its proposal. The palaeontological progress relates to early Homo finds in the Caucasus, Denisova finds in the Altai Mountains and Neanderthal finds in a wide range of localities from the Altai Mountains, the Caucasus, the Levant, Asia Minor, southern and Central Europe and the Iberian Peninsula.
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