Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol.

S Tamura N Fukamiya X Y Mou T Mukainaka H Tokuda H Nishino K Tagahara K Koike K H Lee M Okano

Chem Pharm Bull (Tokyo)

Department of Interdisciplinary Studies of Natural Environment, Faculty of Integrated Arts and Sciences, Hiroshima University, Higashi-Hiroshima, Japan.

Published: June 2000

Introduction of a senecioyl group into shinjulactones B and C, and esterification of the diosphenol moiety in brusatol and brucein A enhanced inhibitory effect against Epstein-Barr virus early antigen activation.

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http://dx.doi.org/10.1248/cpb.48.876	DOI Listing

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