The wound healing and antimicrobial properties of maggots are well known. Maggot debridement therapy has been used for the treatment of various conditions. For maggot debridement therapy, the larvae of the blowfly are applied over necrotic or nonhealing wounds. We used maggot debridement therapy with the larvae of Phaenicia sericata for limb salvage after bilateral lower extremity fourth-degree burns.
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http://dx.doi.org/10.1067/mbc.2000.106659 | DOI Listing |
J Clin Med
January 2025
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
: Larval therapy (LT), an intervention using live fly larvae to remove necrotic tissue and promote healing, has regained attention in order to address the growing need for chronic wound management. LT was approved by the Food and Drug Administration (FDA) in 2004 to treat difficult-to-heal wounds; however, LT remains an underutilized therapy. To evaluate efficacy of LT in a systematic review and meta-analysis of wound outcomes from randomized controlled trials (RCTs).
View Article and Find Full Text PDFSurg Pract Sci
March 2025
Department of Nursing, Zanjan University of Medical Sciences, Zanjan, Iran.
Objective: The objective of this systematic review of case reports is to evaluate the efficacy and safety of combining surgical sharp debridement with maggot debridement therapy (MDT) for the treatment of diabetic foot ulcers (DFUs).
Methods: A comprehensive literature search was conducted across multiple databases, including PubMed, Embase, Cochrane Library, and Web of Science. Inclusion criteria were studies that reported on the use of surgical sharp debridement alongside MDT for DFUs, while exclusion criteria included insufficient detail on treatment methods or patient outcomes, non-human studies, and non-English publications.
Int Wound J
January 2025
Applied BioSciences, Faculty of Science and Engineering, Macquarie University, North Ryde, New South Wales, Australia.
There are two major styles of maggot debridement dressings: (1) confinement dressings that form a cage around the wound, and (2) containment dressings that completely surround the maggots within a sealed porous bag. For producers and clinicians wanting to prepare containment dressings using readily available polyester bags, it is currently difficult to seal these bags without expensive high-temperature plastic welders. This study aimed to identify simple and affordable methods for sealing maggots within polyester net bags.
View Article and Find Full Text PDFJ Wound Care
January 2025
Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Clinical Research Centre, Singapore.
Objective: There is little use of maggot debridement therapy (MDT) worldwide, albeit there is much literature supporting its benefits and effectiveness for hard-to-heal (chronic) wounds. Hard-to-heal wounds are becoming ever more prevalent and MDT can play a pivotal role in wound care management. This underuse can be associated with patients' perceptions and experiences of MDT.
View Article and Find Full Text PDFAdv Skin Wound Care
January 2025
Danique Heuvelings, MD, is Medical Doctor and Surgical PhD Candidate, Department of Surgery, Maastricht University Medical Center, Maastricht, the Netherlands, and NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University. Also at Department of Surgery, Maastricht University Medical Center, Jishmaël van der Horst, MD, is Clinical Specialist, and Fanny Pelzer, MD, is Wound Care Nurse. Frits Aarts, MD, PhD, is Oncological Surgeon, Department of Surgery, VieCuri Medical Centre, Venlo, the Netherlands. Sanne Engelen, MD, PhD, is Oncological Surgeon, Department of Surgery, Maastricht University Medical Center.
Massive localized lymphedema (MLL) is a benign overgrowth of lymphoproliferative tissue that is primarily observed in adults with class III obesity. Patients present with a painless mass that has usually been present for a considerable period. Consultation of a healthcare professional typically takes place when MLL-related complaints interfere with daily living.
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