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Monocyte/Macrophage-Specific Loss of ARNTL Suppresses Chronic Kidney Disease-Associated Cardiac Impairment.
Int J Mol Sci
December 2024
Department of Clinical Pharmacokinetics, Faculty of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Defects in Aryl hydrocarbon receptor nuclear translocator-like 1 (ARNTL), a central component of the circadian clock mechanism, may promote or inhibit the induction of inflammation by monocytes/macrophages, with varying effects on different diseases. However, ARNTL's role in monocytes/macrophages under chronic kidney disease (CKD), which presents with systemic inflammation, is unclear. Here, we report that the expression of in monocytes promoted CKD-induced cardiac damage.
View Article and Find Full Text PDFFood Preference Assessed by the Newly Developed Nutrition-Based Japan Food Preference Questionnaire and Its Association with Dietary Intake in Abdominal-Obese Subjects.
Nutrients
December 2024
Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, 2-2, Yamada-oka, Suita 565-0871, Osaka, Japan.
Background/objectives: Understanding food preferences is important for weight management. However, methods for assessing food preferences are not well established, especially in Japan. This study aimed to examine detailed food preferences and their associations with actual food intake in non-obese and abdominal-obese subjects using a newly developed questionnaire tailored for the Japanese population.
View Article and Find Full Text PDFComparative analysis of heart rate variability indices from ballistocardiogram and electrocardiogram: a study on measurement agreement.
Heart Vessels
December 2024
Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
Ballistocardiogram (BCG) captures minute vibrations generated by heart movements. These vibrations are converted into heart rate variability (HRV) indices, allowing their unobtrusive monitoring over extended periods, while reducing the burden on patients or subjects. In this study, to evaluate the agreement between the HRV indices, we compared the HRV indices estimated from the BCG device with those obtained from the gold standard electrocardiogram (ECG).
View Article and Find Full Text PDFComputed tomography morphological assessments of central airways in interstitial lung abnormalities and idiopathic pulmonary fibrosis.
Respir Res
November 2024
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Background: Little is known about whether central airway morphological changes beyond traction bronchiectasis develop and affect clinical outcomes in patients with idiopathic pulmonary fibrosis (IPF). This study aimed to compare central airway structure comprehensively between patients with IPF, subjects with interstitial lung abnormality (ILA), and those without ILA (control) using computed tomography (CT). We further examined the prognostic impact of IPF-specific CT airway parameters in patients with IPF.
View Article and Find Full Text PDFDiurnal variation in the association between the scan frequency of isCGM and CGM metrics: post hoc analysis of the ISCHIA study.
Diabetol Int
October 2024
Department of Clinical Nutrition, NHO Kyoto Medical Center, Kyoto, Japan.
Article Synopsis
- The study analyzed data from 93 participants with type 1 diabetes to explore how the frequency of scanning with intermittent-scanning continuous glucose monitoring (isCGM) affects time in range (TIR), time above range (TAR), and time below range (TBR) throughout the day.
- Increased scanning frequency was linked to higher TIR, particularly in the afternoon, evening, and night, and was associated with lower TAR and TBR during these times.
- Psychological factors, such as concerns about blood glucose levels affecting social interactions and feelings of loneliness, were found to influence how often participants scanned their glucose levels.
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