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Localized inflammatory reactions in patients with past procedural history of intradermal injections can quickly drive the clinician's attention towards a diagnosis of soft-tissue infection in the context of symptoms such as fever, malaise, and local induration of the adipose panniculus. However, in patients with a long-term history of granulomatous events, a rheumatologic approach must be taken into consideration when the clinical course overwhelms the odds for more conventional diagnoses. In this case, a 39-year-old female patient who underwent bilateral lower limbs intradermal filllers presented with a two-year clinical course of repetitive flares of external bilateral hip tenderness, pain that limits her walking, soft-tissue nodular inflammation, redness, fever and a soft mobile nonpainful right supraclavicular lymphadenopathy.

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: Anti PD1/PD-L1 agents, including pembrolizumab, have revolutionized the oncological treatment of different types of cancer, including non-small cell lung cancer. The most frequent complications associated with this type of treatment are mild and are located at the thyroid, pulmonary or hepatic level. Sarcoid like reaction and mesenteric panniculitis secondary to pembrolizumab treatment are two very rare adverse effects.

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[Erythema nodosum].

Dermatologie (Heidelb)

January 2025

Dermatologische Klinik, Universitätsspital Zürich, Rämistr. 100, 8901, Zürich, Schweiz.

Erythema nodosum (EN) is the most frequently occurring form of acute panniculitis. It is characterized by painful red to livid raised nodules or bumps that typically occur symmetrically in the shin area. The cause of EN is often a reaction of the immune system to various triggers including infections, inflammatory diseases or medications.

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A Rare Case of Concurrent Lupus Mastitis and Sarcoidosis in a 62-Year-Old Female.

Eur J Breast Health

July 2024

Department of Radiology University of Miami Miller School of Medicine, Sylvester Cancer Center, and Jackson Memorial Hospital, Miami, FL, USA.

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  • * A 62-year-old woman with discoid lupus and Graves' disease had an abnormal mammogram that led to a biopsy revealing lupus mastitis, along with features of sarcoidosis.
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[Erythema nodosum].

Z Rheumatol

October 2024

Dermatologische Klinik, Universitätsspital Zürich, Rämistr. 100, 8901, Zürich, Schweiz.

Erythema nodosum (EN) is the most frequently occurring form of acute panniculitis. It is characterized by painful red to livid raised nodules or bumps that typically occur symmetrically in the shin area. The cause of EN is often a reaction of the immune system to various triggers including infections, inflammatory diseases or medications.

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