Background: All patients who underwent trans-sphenoidal surgery between January 1984 and December 1998 were reviewed to assess morbidity resulting from this operation.
Methods: There were 185 operations on 165 patients. The operative approach was sublabial in 80 cases and transnasal in 105. One surgeon (VB) performed the vast majority of operations.
Results: Complications included nasal perforation (7.6%), transient diabetes insipidus (4.9%), permanent diabetes insipidus (3.8%), cerebrospinal fluid fistula (4.3%), donor site haematoma (2.2%) and residual tumour haemorrhage (1.6%) causing ophthalmoplegia (1.1%) and loss of vision (1.1%). Other complications included epistaxis (1.1%), meningitis (0.5%) and sinusitis (0.5%). Injury to the anterior superior alveolar nerve also occurred in the sublabial approach in 6.3% of patients. There were no perioperative deaths.
Conclusions: There is a small but significant risk of a number of complications that should be considered for informed consent of this procedure.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1046/j.1440-1622.2000.01843.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Growth Hormone-Secreting Pituitary Adenoma: Dura Mater Invasion Is Not a Predictor of Acromegaly Persistence After Trans-Sphenoidal Surgery.
J Clin Med
December 2024
Skull Base and Pituitary Surgery Unit, "Città della Salute e della Scienza" University Hospital, 10126 Turin, Italy.
: In pituitary adenomas, examinations of surgical specimens have shown that dural invasion occurs in 42-85% of cases. No studies about dura mater invasion have been conducted specifically in acromegaly patients. The aim of the present study was to evaluate the relationship between histologically dural invasion and the main features of GH-secreting adenomas.
View Article and Find Full Text PDFMassive pneumocephalus after Valsalva maneuver in sphenoidal meningocele.
J Clin Neurosci
December 2024
Department of Otorhinolaryngology-Head and Neck Surgery, University of Insubria, Varese, Italy; Head and Neck Surgery & Forensic Dissection Research Center (HNS&FDRc), Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
Pneumocephalus, defined as the presence of gas within the intracranial space, typically results from head trauma, surgery, or diagnostic/therapeutic procedures that disrupt the dura. However, spontaneous or non-traumatic pneumocephalus is rare. This video article presents a case report of a 64-year-old woman referred to the Department of Otolaryngology with a severe frontal headache and clear nasal discharge (rhinorrhea) after performing the Valsalva maneuver to relieve ear fullness.
View Article and Find Full Text PDFSurgical treatment of tuberculum sellae meningioma: A retrospective review of single institutional experience.
Surg Neurol Int
November 2024
Department of Neurosurgery, Dr. Hasan Sadikin Hospital, Padjadjaran University, Bandung, West Java, Indonesia.
Background: Tuberculum sellae meningiomas (TSMs) represent a distinct entity among intracranial meningiomas. Both transcranial approaches (TCAs) and endoscopic endonasal approaches (EEAs) have provided neurosurgeons with options for managing these difficult tumors. Still, controversies persist regarding the selection criteria for the most optimal approach.
View Article and Find Full Text PDFAssessment of the initial results of pituitary tumor registry at a tertiary hospital of Iran: 2009-2022.
J Diabetes Metab Disord
December 2024
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Shariati Hospital, Fifth Floor, North Kargar Ave, Tehran, Iran.
Objectives: The Pituitary Tumor Registry intends to provide a platform for clinical research and basic sciences, with an emphasis on disease outcomes.
Methods: In this retrospective cohort study, all patient data, including demographics, vital signs, symptoms and signs, medical history, medications, past drug history, paraclinical data, treatment modalities, post-surgery follow-up, treatment responsiveness, and pathology reports, have been gathered from the electronic patient records of the Endocrinology and Metabolism Research Center affiliated with Tehran University of Medical Sciences.
Results: A total of 200 patients with pituitary adenoma were identified.
Article Synopsis
- The study examined the use of Endoscopic Endonasal Trans-Sphenoidal Approach (EETA) for removing skull base tumors, specifically macro-adenomas, and assessed its effectiveness in terms of tumor resection and recurrence rates.
- Conducted over two years with 58 patients aged around 47, the results indicated a high success rate, with 84.4% achieving complete tumor removal, while 15.6% experienced recurrence.
- The findings suggest that EETA is a safe and effective method for treating macroadenomas, significantly contributing to the surgical management of these tumors.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!