Brainstem auditory evoked potentials (BAEP) were examined in 40 patients with subjective disorders following closed head injury (CHI), with the established degree of recovery and performed CT-scan of the head. For all BAEP parameters the interval of normality was defined as 3 SD above and below mean value in the control group comprised of 20 healthy subjects. The upper limits of thus defined intervals of normality enabled the formation of four types of findings: type 1--normal finding that was registered in 23 (57.5%) patients; type 2 was a sum of individual findings with the prolonged interpeak latencies, but without the change of relative amplitude V:I--7 (17.5%) recordings; type 3--the findings where the fall of relative amplitude V:I was registered together with the prolongation of interpeak latency. It comprised of 4 (10%) recordings and the type 4 included 6 (15%) individual recordings with registered low RA V:I (0.8 or lower). The explanation of the most probable genesis of registered changes was presented.
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Otolaryngol Head Neck Surg
January 2025
Division of Otolaryngology, Children's National Hospital, Washington, DC, USA.
Objective: Despite significant improvements in universal newborn hearing screenings (NBHS), infants are still lost to follow-up (LTF) after failed screening, delaying timely diagnosis and intervention. The challenges during the COVID-19 pandemic and its response likely exacerbated timely adherence to early diagnosis and intervention. This study aimed to assess the LTF rate for infants who did not pass their NBHS within Washington, DC and compare the LFT before and during the pandemic.
View Article and Find Full Text PDFExp Eye Res
January 2025
Shenzhen Eye Hospital, Jinan University, Shenzhen Eye Institute, Shenzhen, 518040 Guangdong, China. Electronic address:
Usher syndrome is a rare autosomal recessive genetic disorder that primarily affects both vision and hearing, manifesting as sensorineural hearing loss and progressive vision loss caused by retinitis pigmentosa. The pathogenesis of retinal degeneration in Usher syndrome is still largely unknown. In this study, a novel Ush2a knockout mouse model was successfully constructed using CRISPR/Cas9 technology.
View Article and Find Full Text PDFPLoS One
January 2025
Institute of Endocrinology, Prague, Czech Republic.
Objectives: Hearing impairment can have major impacts on behavior, educational attainment, social status, and quality of life. In congenital hypothyroidism, the incidence of hearing impairment reaches 35-50%, while in acquired hypothyroidism there is a reported incidence of 25%. Despite this, knowledge of the pathogenesis, incidence and severity of hearing impairment remains greatly lacking.
View Article and Find Full Text PDFJ Neurol Surg B Skull Base
February 2025
Department of Neurosurgery, UC San Diego Medical Center, San Diego, California, United States.
Many patients with neurofibromatosis type 2 (NF2) suffer from sensorineural hearing loss, and associated cochlear nerve compromise in NF2 patients makes auditory brainstem implant (ABI) an attractive treatment option. The long-term outcomes and benefits of the device are still being explored. A retrospective review was conducted for 11 ABI recipients at a single-institution tertiary center between November 2017 and August 2022.
View Article and Find Full Text PDFInt J Audiol
January 2025
Department of Audiology, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.
Objective: Tinnitus and its pathophysiological mechanisms need more investigation because tinnitus may change the typical processing of sounds in the auditory system. Poor temporal resolution, which is not assessed with conventional subjective tinnitus evaluations, has been reported in some tinnitus sufferers.
Design: This study used a gap-in-noise paradigm to assess temporal resolution in tinnitus sufferers using both behavioural and electrophysiologic methods.
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