Clinical and experimental data are reviewed on the Reye's syndrome--a heavy complication accompanying the therapy of viral infections in children by salicylates. Disorders in the bioenergetics of fatty acid oxidation and ammonia utilization are considered in the context of clinical manifestations of the Reye's syndrome.
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Griscelli syndrome: a case report of Reye's syndrome and atopic dermatitis history.
J Indian Soc Pedod Prev Dent
March 2009
Suleyman Demirel University, Faculty of Dentistry, Department of Pediatric Dentistry Isparta, Turkey.
Griscelli syndrome (GS) is a rare autosomal recessive disorder that results in pigmentary dilution of the skin and the hair (silver hair), with the presence of large clumps of pigment in hair shafts, and an accumulation of melanosomes in melanocytes. Sixty cases of GS have been reported in the literature, but we could find no description of its oro-dental symptoms. Reye's syndrome (RS) is characterized by acute noninflammatory encephalopathy and renal and hepatic failure, while atopic dermatitis (AD) is a skin disorder with an immunologic basis.
View Article and Find Full Text PDFIs aspirin a cause of Reye's syndrome? A case against.
Drug Saf
September 2002
Pediatric Intensive Care Unit, University Community Hospital, Tampa, Florida 33613, USA.
Article Synopsis
- * No evidence has been found of salicylates in the blood or urine of affected patients, and no animal models show that aspirin can trigger the disease.
- * The decline in Reye's syndrome cases began prior to any warnings about aspirin, suggesting it might have been a viral mutation or a collection of metabolic disorders misidentified at the time.
[Reye's syndrome--a severe complication of salicylate therapy].
Eksp Klin Farmakol
July 2000
Pharmacology Department, Siberian Medical University, Tomsk, Russia.
Clinical and experimental data are reviewed on the Reye's syndrome--a heavy complication accompanying the therapy of viral infections in children by salicylates. Disorders in the bioenergetics of fatty acid oxidation and ammonia utilization are considered in the context of clinical manifestations of the Reye's syndrome.
View Article and Find Full Text PDF[Reye syndrome: a case study in a Cuban provincial hospital from 1990 to 1996].
Rev Neurol
December 1999
Hospital Provincial Pediátrico Docente Pepe Portilla, Pinar del Rio, Cuba.
Introduction: Reye's syndrome is a metabolic encephalopathy of infancy which is often fatal. Epidemiological studies have shown associated factors including having taken Aspirin for viral illness. Some patients with this disorder may have preexisting organic acidemia such as dicarboxylic aciduria.
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