Enrofloxacin metabolism by Mucor ramannianus was investigated as a model for the biotransformation of veterinary fluoroquinolones. Cultures grown in sucrose-peptone broth were dosed with enrofloxacin. After 21 days, 22% of the enrofloxacin remained. Three metabolites were identified: enrofloxacin N-oxide (62% of the total absorbance), N-acetylciprofloxacin (8.0%), and desethylene-enrofloxacin (3.5%).
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC110597 | PMC |
| http://dx.doi.org/10.1128/AEM.66.6.2664-2667.2000 | DOI Listing |
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