Lower rim functionalized resorcinarenes: useful modules for supramolecular chemistry.

Org Lett

Skaggs Institute for Chemical Biology, Scripps Research Institute, La Jolla, California 92037, USA.

Published: October 1999

AI Article Synopsis

Article Abstract

[formula: see text] A synthetic scheme for the selective functionalization of all-cis (rccc) resorcinarene platform at the "lower rim" was developed. Self-folding and self-complementary cavitands were prepared for molecular recognition and self-assembly, bearing functionality at remote sites. These molecules promise applications on solid support and as polymeric capsules.

Download full-text PDF

Source
http://dx.doi.org/10.1021/ol9902125DOI Listing

Publication Analysis

Top Keywords

lower rim
4
rim functionalized
4
functionalized resorcinarenes
4
resorcinarenes modules
4
modules supramolecular
4
supramolecular chemistry
4
chemistry [formula
4
[formula text]
4
text] synthetic
4
synthetic scheme
4

Similar Publications

A Veteran Presenting With Fatigue and Weakness.

Fed Pract

October 2024

Veterans Affairs Boston Healthcare System, West Roxbury, Massachusetts.

: A 65-year-old male veteran presented to the Veterans Affairs Boston Healthcare System (VABHS) emergency department with progressive fatigue, dyspnea on exertion, lightheadedness, and falls over the last month. New bilateral lower extremity numbness up to his knees developed in the week prior to admission and prompted him to seek care. Additional history included 2 episodes of transient loss of consciousness resulting in falls and a week of diarrhea, which had resolved.

View Article and Find Full Text PDF

Background/ Aims: To analyze the longitudinal change in Bruch's membrane opening minimal rim width (BMO-MRW) and peripapillary retinal nerve fiber layer (pRNFL) thickness using optical coherence tomography (OCT) after implantation of a PRESERFLO® microshunt for surgical glaucoma management in adult glaucoma patients.

Methods: Retrospective data analysis of 59 eyes of 59 participants undergoing implantation of a PRESERFLO microshunt between 2019 and 2022 at a tertiary center for glaucoma management. Surgical management included primary temporary occlusion of the glaucoma shunt to prevent early hypotony.

View Article and Find Full Text PDF

Background: In multiple sclerosis (MS), susceptibility-weighted imaging (SWI) may reveal white matter lesions (WML) with a paramagnetic rim ("paramagnetic rim lesions" [PRLs]) or diffuse hypointensity ("core-sign lesions"), reflecting different stages of WML evolution.

Objective: Using the soma and neurite density imaging (SANDI) model on diffusion-weighted magnetic resonance imaging (MRI), we characterized microstructural abnormalities of MS PRLs and core-sign lesions and their clinical relevance.

Methods: Forty MS patients and 20 healthy controls (HC) underwent a 3 T brain MRI.

View Article and Find Full Text PDF

The correlation between clinical outcomes and preoperative/postoperative measures of the lateral center-edge angle (LCEA) will help establish the cutoff values for this measurement and determine whether to obtain it from the lateral acetabular rim (LCEAR) or the lateral end of the sourcil (LCEAS). The hypothesis was that the LCEAS would be more sensitive than the LCEAR. An upper cutoff value of LCEA could predict better functional outcomes in FAI patients.

View Article and Find Full Text PDF

Differential determinants and prognostic value of aortic valve sclerosis over carotid atherosclerosis.

Int J Cardiol

January 2025

Division of Cardiology, Heart Center, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

Background: Aortic valve sclerosis (AVS) is a progressive atherosclerotic disease associated with future cardiovascular events (CVE). However, whether its development and prognostic value are independent of arterial atherosclerosis has not been thoroughly investigated. We evaluated the determinants and prognostic value of AVS in conjunction with carotid atherosclerosis.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!