Cops and robbers: putative evolution of copper oxygen-binding proteins.

J Exp Biol

Institute for Molecular Biophysics, University of Mainz, Germany.

Published: June 2000

Two closely related copper proteins, phenoloxidase and haemocyanin, are known to be involved in different physiological functions such as the primary immune response and oxygen transport. Although the proteins differ structurally, they have the same active site by which dioxygen is bound. Recent results reveal that haemocyanin also exhibits phenoloxidase activity. A scenario is proposed for the evolutionary relationships among copper oxygen-binding proteins (COPs).

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http://dx.doi.org/10.1242/jeb.203.12.1777DOI Listing

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