[reaction: see text] An efficient method has been developed for the stereoselective bis-functionalization of arene chromium tricarbonyl complexes. Initial nucleophilic addition of organolithium reagents to a carbonyl moiety is followed by a 1,4-carbon to oxygen silyl migration (Brook rearrangement) and alkylation of the resultant aryl anion.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ol0056022 | DOI Listing |
Publication Analysis
Top Keywords
arene chromium
8
chromium tricarbonyl
8
tricarbonyl complexes
8
stereoselective bis-functionalizations
4
bis-functionalizations arene
4
complexes brook
4
brook rearrangements
4
rearrangements [reaction
4
[reaction text]
4
text] efficient
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!