Multiple carcinoid tumors of the small bowel with more than 3 lesions are very unusual. The authors report a case with 4 lesions, 2 of those localized in the jejunum with more advanced infiltration of the wall and extension to regional mesenteric lymph nodes, revealed by ultrasonography. The relative low incidence and particularly the vague, nonspecific clinical presentation, the unusual site in the jejunum, and failure of the radiological examine of one year before lead to not suspect this condition prior to US examination. However, the feature of asymmetric, concentric thickening of the bowel wall requiring a more accurate exam by CT with oral contrast was able to confirm the suspect of the intestinal tumor. The patient, 80 year old, underwent radical surgery with a wide lymph nodes dissection as well as double resection of the jejunum and distal ileum. The post-surgical outcome was uneventful. A 12-month follow-up is free of the disease.
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AAPS J
January 2025
Certara UK Limited, Level 2, Acero, 1 Concourse Way, Sheffield, S1 2BJ, UK.
Bile salts are biosurfactants released into the intestinal lumen which play an important role in the solubilisation of fats and certain drugs. Their concentrations vary along the gastrointestinal tract (GIT). This is significant for implementation in physiologically based pharmacokinetic (PBPK) modelling to mechanistically capture drug absorption.
View Article and Find Full Text PDFFront Microbiol
December 2024
VERO Program, Texas A&M University, Canyon, TX, United States.
Introduction: The gastrointestinal microbiota profoundly influences the health and productivity of animals. This study aimed to characterize microbial community structures of the mouth, gastrointestinal tract (GIT), and feces of cattle.
Methods: Samples were collected from 18 Akaushi crossbred steers at harvest from multiple locations, including the oral cavity, rumen, abomasum, duodenum, jejunum, ileum, cecum, spiral colon, distal colon, and feces.
World J Gastrointest Surg
November 2024
Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Background: Non-ulcerative necrosis of the stomach and duodenum is rare because of the abundant blood supply in the gastrointestinal tract. Duodenal necrosis is a rare complication of severe acute pancreatitis. Emergency pancreaticoduodenectomy (EPD) is a rare procedure, with extensive duodenal necrosis being one of its indications.
View Article and Find Full Text PDFPediatr Surg Int
December 2024
Division of Pediatric Surgery, Stanford University, Stanford, CA, USA.
Purpose: We aim to apply our spring-mediated intestinal lengthening technique to adults and children with short bowel syndrome. We hypothesized that spring-mediated intestinal lengthening would be achieved in adult and juvenile pigs.
Methods: Adult and juvenile pigs underwent insertion of a compressed spring into the jejunum.
Poult Sci
January 2025
College of Animal Science and Technology, Yangzhou University, 48 Wenhui East Road, Yangzhou, Jiangsu Province 225009, China. Electronic address:
The current study aimed to explore the suitable starch: protein ratios under different dietary protein levels for goslings. A total of 360 male 1-day-old Jiangnan White goslings were randomly divided into 6 groups with six replicates containing ten goslings each. The experimental design consisted of a 3 × 2 factorial array of treatments.
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