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Insights and Opportunities from Multimarker Evaluation of Heart Failure: Lessons from BIOSTAT-HF.
Curr Heart Fail Rep
January 2025
Division of Cardiovascular Medicine, Department of Medicine, University of California, 9394 Medical Center Drive, La Jolla, San Diego, CA, USA.
Purpose Of Review: Heart failure is a complex and heterogenous disease state that affects millions worldwide. Over recent decades, advancements in medical therapy and device implementation have significantly transformed the landscape of heart failure outcomes, while improvements in imaging modalities and greater accessibility to genome sequencing have led to increasing recognition of distinct heart failure endotypes. There is rising evidence to suggest all patients do not benefit equally from intensification of guideline directed medical therapy (GDMT).
View Article and Find Full Text PDFThe misalignment of incentives in academic publishing and implications for journal reform.
Proc Natl Acad Sci U S A
February 2025
Department of Data and Decision Science, Technion-Israel Institute of Technology, Haifa 3200003, Israel.
For most researchers, academic publishing serves two goals that are often misaligned-knowledge dissemination and establishing scientific credentials. While both goals can encourage research with significant depth and scope, the latter can also pressure scholars to maximize publication metrics. Commercial publishing companies have capitalized on the centrality of publishing to the scientific enterprises of knowledge dissemination and academic recognition to extract large profits from academia by leveraging unpaid services from reviewers, creating financial barriers to research dissemination, and imposing substantial fees for open access.
View Article and Find Full Text PDFRecovery of Bioactive Constituents from Olive Leaf Pruning Waste of Five Different Cultivars: A Comparison of Green Extraction Techniques to Maximize Health Benefits.
Foods
January 2025
Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", Via Vivaldi 43, 81100 Caserta, Italy.
Sustainable agro-waste revaluation is critical to enhance the profitability and environmental footprint of the olive oil industry. Herein, the valorization of olive leaf pruning waste from five cultivars ('Caiazzana', 'Carolea', 'Itrana', 'Leccino', and 'Frantoio') employed green extraction methods to recover compounds with potential health benefits. Sequential ultrasound-assisted maceration (UAM) in -hexane and ethanol was compared with a compressed fluid extraction strategy consisting of supercritical fluid extraction (SFE) and pressurized liquid extraction (PLE) for their efficiency in recovering distinct classes of bioactives.
View Article and Find Full Text PDFVibration Foam Rolling Treatment Influence on Acute Changes in Plantar Flexors Muscle Temperature and Surface Emg Activity in Amateur Male Athletes.
J Funct Morphol Kinesiol
January 2025
Faculty of Sport and Physical Education, University of Belgrade, 11000 Belgrade, Serbia.
Foam rolling is widespread and deeply rooted in exercise practice. The optimal duration and role of this treatment still lack scientific consensus. A relatively novel foam rolling treatment that combines vibration during application targets different muscle characteristics that are not well understood.
View Article and Find Full Text PDFIncompatible Aedes aegypti male releases as an intervention to reduce mosquito population-A field trial in Puerto Rico.
PLoS Negl Trop Dis
January 2025
Division of Vector Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.
Mosquito-transmitted viruses such as dengue are a global and growing public health challenge. Without widely available vaccines, mosquito control is the primary tool for fighting the spread of these viruses. New mosquito control technologies are needed to complement existing methods, given current challenges with scalability, acceptability, and effectiveness.
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