Using data collected in a study of arrested youths processed at a juvenile assessment center who entered a home-based family intervention project, the authors test a three-stage longitudinal model. The model reflects a developmental damage view of the relationships of the youths' family problems (including their physical abuse and sexual victimization experiences) to their drug use and delinquent behavior over time. The hypothesized model is supported by the data. Research, theoretical, and policy implications of the results are drawn.
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http://dx.doi.org/10.1080/02791072.2000.10400212 | DOI Listing |
JAMA Netw Open
January 2025
Department of Obstetrics and Gynecology, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York.
Importance: Understanding environmental risk factors for gestational diabetes (GD) is crucial for developing preventive strategies and improving pregnancy outcomes.
Objective: To examine the association of county-level radon exposure with GD risk in pregnant individuals.
Design, Setting, And Participants: This multicenter, population-based cohort study used data from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be (nuMoM2b) cohort, which recruited nulliparous pregnant participants from 8 US clinical centers between October 2010 and September 2013.
EJNMMI Radiopharm Chem
January 2025
Division of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Background: Poly (ADP-ribose) polymerase (PARP) enzymes are crucial for the repair of DNA single-strand breaks and have become key therapeutic targets in homologous recombination-deficient cancers, including prostate cancer. To enable non-invasive monitoring of PARP-1 expression, several PARP-1-targeting positron emission tomography (PET) tracers have been developed. Here, we aimed to preclinically investigate [carbonyl-C]DPQ as an alternative PARP-1 PET tracer as it features a strongly distinct chemotype compared to the frontrunners [F]FluorThanatrace and [F]PARPi.
View Article and Find Full Text PDFVis Comput Ind Biomed Art
January 2025
School of Engineering Medicine and School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China.
Fluorescence endoscopy technology utilizes a light source of a specific wavelength to excite the fluorescence signals of biological tissues. This capability is extremely valuable for the early detection and precise diagnosis of pathological changes. Identifying a suitable experimental approach and metric for objectively and quantitatively assessing the imaging quality of fluorescence endoscopy is imperative to enhance the image evaluation criteria of fluorescence imaging technology.
View Article and Find Full Text PDFOdontology
January 2025
Oral Biology Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
Natural bone is a self-regenerating nanocomposite made of proteins and minerals. Such self-regenerative capacity can be negatively affected by certain diseases involving the bone or its surrounding tissues. Our study assesses the ability of bone grafting material to regenerate bone in animals who have artificially created critical-sized defects.
View Article and Find Full Text PDFEnviron Monit Assess
January 2025
Department of Chemistry, Vaal University of Technology, Vanderbijlpark, South Africa.
Due to incessant contamination of the groundwater system near the dumpsite in southwestern Nigeria Basement Complex, this study seeks to evaluate the impact of the Odogbo dumpsite on the local groundwater system by integrating geophysical and geochemical methodologies. Aeromagnetic data covering the study area was acquired, processed, and enhanced to delineate basement features that could potentially be passing plumes to the groundwater system. Concurrently, geoelectric methods using 2-D dipole-dipole imaging and vertical electrical sounding (VES) were utilized to characterize the vulnerability indices of the lithologies underlying the dumpsite.
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