An outbreak of a haemorrhagic enteropathy in a closed herd of pigs was followed by the appearance, in the same herd, of cases of intestinal adenomatosis. This paper now draws attention to similarties in the mucosal pathology which are present in the two conditions. The affected tissue showed substantial epithelial proliferation and retrospective electron microscopic studies of material from both these entities revealed the presence of bacteria of similar morphology within the cytoplasm of these epithelial cells.
Download full-text PDF |
Source |
---|
Fam Cancer
November 2024
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Background: Familial adenomatous polyposis (FAP) predisposes individuals to duodenal adenomas. This study describes the histopathological features of endoscopic and surgical specimens from the duodenum, as well as genotype-phenotype associations.
Methods: All known FAP patients were included from the Danish Polyposis Register.
World J Clin Cases
December 2022
Department of Gastroenterology, China-Japan Friendship Hospital, Beijing 100029, China.
Background: Whipple's disease is a rare systemic infection caused by . Most patients present with nonspecific symptoms, and routine laboratory and imaging examination results also lack specificity. The diagnosis often relies on invasive manipulation, pathological examination, and molecular techniques.
View Article and Find Full Text PDFCancer Commun (Lond)
December 2022
Department of Pathology, State Key Laboratory of Complex Severe and Rare Diseases, Molecular Pathology Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, P. R. China.
Background: Neuroendocrine carcinomas of the gastrointestinal tract (GI-NECs) remain a disease of grim prognosis with limited therapeutic options. Their molecular characteristics are still undefined. This study aimed to explore the underlying genetic basis and heterogeneity of GI-NECs.
View Article and Find Full Text PDFFam Cancer
October 2022
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Germline biallelic pathogenic variants (PVs) in NTHL1 have since 2015 been associated with the autosomal recessive tumor predisposition syndrome: NTHL1 tumor syndrome or NTHL1-associated polyposis. In this systematic review, we aim to systematically investigate the phenotypic and genotypic spectrum of the condition including occurrence of both benign and malignant tumors. The databases PubMed, EMBASE, and Scopus were searched.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!