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Global burden of cancer pattern in 2020 & prediction to 2040 among older adults.
Indian J Med Res
November 2024
ICMR-Centre for Ageing & Mental Health, Kolkata, West Bengal, India.
Background & objectives Cancer is one of the leading causes of death among older adults worldwide. The global burden of cancer among older individuals is increasing due to the ageing population. The increasing burden of cancer among older adults will pose significant social and economic challenges for the delivery of healthcare services.
View Article and Find Full Text PDFCoupling coordination relationship between health resource allocation and regional economic development: an empirical study based on five provinces in eastern China.
Front Public Health
December 2024
School of Public Health, Shandong Second Medical University, Weifang, China.
Background: Improving system coordination is a pivotal strategy and a critical pathway for social governance. Chinese society is currently facing a significant challenge in aligning the allocation of health resources with economic development. Evaluating the level of coordinated development within the system can provide valuable insights to support the construction of a more coordinated China and foster high-quality development.
View Article and Find Full Text PDFResearch on adverse event classification algorithm of da Vinci surgical robot based on Bert-BiLSTM model.
Front Comput Neurosci
December 2024
School of Health Sciences and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
This study aims to enhance the classification accuracy of adverse events associated with the da Vinci surgical robot through advanced natural language processing techniques, thereby ensuring medical device safety and protecting patient health. Addressing the issues of incomplete and inconsistent adverse event records, we employed a deep learning model that combines BERT and BiLSTM to predict whether adverse event reports resulted in patient harm. We developed the Bert-BiLSTM-Att_dropout model specifically for text classification tasks with small datasets, optimizing the model's generalization ability and key information capture through the integration of dropout and attention mechanisms.
View Article and Find Full Text PDFA phase I study using bortezomib (Velcade), cladribine, and rituximab in treating patients over 50 years old with mantle cell lymphoma.
Front Oncol
December 2024
Penn State Hershey Cancer Institute, Pennsylvania State University College of Medicine, Hershey, PA, United States.
Unlabelled: Cladribine indirectly downregulates methylation of DNA, RNA, and histones by blocking the transfer of methyl groups from -adenosyl-methionine. The cladribine and rituximab combination showed a synergetic effect in treating B-cell lymphomas. Bortezomib (Velcade) is a Food and Drug Administration (FDA)-approved proteasome inhibitor for treating mantle cell lymphoma (MCL).
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