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Interpretable COVID-19 chest X-ray detection based on handcrafted feature analysis and sequential neural network.
Comput Biol Med
January 2025
University of Rwanda, Rwanda. Electronic address:
Deep learning methods have significantly improved medical image analysis, particularly in detecting COVID-19 chest X-rays. Nonetheless, these methodologies frequently inhibit some drawbacks, such as limited interpretability, extensive computational resources, and the need for extensive datasets. To tackle these issues, we introduced two novel algorithms: the Dynamic Co-Occurrence Grey Level Matrix (DC-GLM) and the Contextual Adaptation Multiscale Gabor Network (CAMSGNeT).
View Article and Find Full Text PDFAutoimmune pulmonary alveolar proteinosis developed during treatment for systemic sclerosis: a case report.
BMC Pulm Med
January 2025
Department of Pulmonary Medicine, National Hospital Organization MinamiKyushu Hospital, 1882 Kida, Aira-Shi, Kagoshima, 899-5293, Japan.
Background: Reports of autoimmune diseases coexisting with autoimmune pulmonary alveolar proteinosis (autoimmune PAP; APAP) are extremely rare. APAP coexisting with autoimmune diseases may often be misdiagnosed as connective tissue disease-associated interstitial lung disease (ILD). Here, we describe a rare case of a patient with systemic sclerosis who was diagnosed with APAP after the exacerbation of lung opacities during treatment with immunosuppressive agents.
View Article and Find Full Text PDFRituximab Therapy in Pulmonary Alveolar Proteinosis: A Case Report.
Cureus
November 2024
Department of Pulmonology, Centre Hospitalier Universitaire (CHU) Mohammed VI, Arrazi Hospital, Faculté de Médecine et de Pharmacie de Marrakech, Laboratoire de Recherche Morpho Sciences, Université Cadi Ayyad (FMPM, Labo LRMS, UCA), Marrakech, MAR.
Autoimmune pulmonary alveolar proteinosis (PAP) is a rare lung condition characterized by the accumulation of surfactant proteins within the alveoli, leading to respiratory distress. We describe a 49-year-old female homemaker with a history of passive smoking and exposure to wood smoke and pigeon droppings. She presented with a dry cough and progressive dyspnea, experiencing significant deterioration in her condition over one year.
View Article and Find Full Text PDFClinical approach for pulmonary alveolar proteinosis in children.
World J Clin Cases
October 2024
Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Article Synopsis
- - Pulmonary alveolar proteinosis (PAP) is a rare lung condition marked by excessive surfactant buildup in the alveoli and is classified into four categories: primary, secondary, congenital, and unclassified.
- - The primary form is linked to issues with the GM-CSF receptor, with autoimmune and hereditary subtypes, while secondary PAP arises from various conditions affecting macrophages, and congenital PAP is caused by genetic mutations.
- - Diagnosis involves specific imaging features and bronchoalveolar lavage, while treatment typically includes whole lung lavage alongside targeted therapies depending on the underlying cause.
Autoimmune pulmonary alveolar proteinosis presenting as localized multifocal GGOs: A case report.
Radiol Case Rep
December 2024
Department of Clinical Oncology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki 852-8501, Japan.
Article Synopsis
- Pulmonary alveolar proteinosis (PAP) is a rare lung disease caused by the buildup of surfactant in the alveoli, often identified by a specific "crazy-paving" pattern on CT scans.
- An 80-year-old woman presented with multiple localized ground glass opacities (GGOs) on CT, which raised suspicion of pulmonary adenocarcinoma due to one lesion's growth.
- After surgery (right upper lobectomy), the diagnosis of PAP was confirmed despite the unusual appearance of the GGOs, emphasizing the need to consider PAP in similar cases.
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