Objectives: To evaluate the radiological miliary shadows in the high landers of a Himalayan desert for the presence of silicosis.
Methods: Seventeen high landers attending the Medicine OPD of a multi-speciality medical camp at Kaza in Himalayas (height 12,500 feet above sea level) having radiological miliary shadows were included in the study. A detailed life time work place history was taken. In the laboratory workup their hemogram, repeat chest skiagram, peak expiratory flow rate, urinalysis and electrocardiogram were undertaken. Their localities were looked for the presence of industries particularly for silicosis prone work place. The silica contents of upper strata of soil were estimated.
Results: Silicosis--chronic simple variety was present in nine males and eight females. The youngest person was 43 years of age and oldest person was of 65 years of age. There was no silicosis prone industry in their locality. Four had taken repeated courses of anti-tubercular treatment in adequate doses for these miliary shadows without any change in the radiological shadows. Three had silicosis prone work history. Seven were smokers and two had hypertension. The miliary shadows were 2-4 mm in size and hilar lymphadenopathy was in 11 and fine calcification of lymph nodes in two. Peak expiratory flow rate was reduced. Upper strata of soil had a silica content of 36.8 percent.
Conclusion: Silicosis developed in high landers of the Himalayas even without working in silicosis prone work place. They were exposed to silica from the non-work place silica rich environment.
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J Glob Infect Dis
May 2024
Department of Radiology, AIIMS, Bilaspur, Himachal Pradesh, India.
Miliary tuberculosis (TB) can occasionally lead to acute respiratory distress syndrome (ARDS) and disseminated intravascular coagulation (DIC). In this case report, we present the case of an 18-year-old male who was diagnosed with miliary TB based on miliary shadows on X-ray and computed tomography of the chest, as well as positivity for mycobacterium TB in endotracheal aspirate by cartridge-based nucleic acid amplification. The patient's hospital stay was complicated by ARDS and DIC, which was successfully managed with ventilatory support, administration of antitubercular treatment, systemic corticosteroids, and blood products.
View Article and Find Full Text PDFCureus
June 2024
Ophthalmology, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.
Disseminated tuberculosis (TB) is a life-threatening disease caused by the hematogenous spread of Mycobacterium tuberculosis. Acute loss of vision as a symptom of disseminated TB is uncommon, as per the literature. Uveitis is the most common ocular manifestation of TB, and tubercular retinal arterial or venous occlusion, with or without ocular signs, has been rarely described before.
View Article and Find Full Text PDFRespir Med Case Rep
March 2024
Department of Oncology, Hangzhou Cancer Hospital, Hangzhou, Zhejiang, 310000, PR China.
Clin J Gastroenterol
June 2024
Department of Radiology, Juntendo University School of Medicine, Tokyo, Japan.
The patient was an 81-year-old man. In his 20s, he had been treated with pharmacotherapy for pulmonary tuberculosis for 1 year. He presented to the Department of Respiratory Medicine with a chief complaint of dyspnea.
View Article and Find Full Text PDFNeuroradiol J
October 2024
Department of Forensic Medicine and Toxicology, King George's Medical University, India.
Objective: This systematic review aimed to evaluate the published cases with miliary brain lesions and their etiological factors, clinical manifestations, diagnostic procedures, and outcomes.
Methods: A comprehensive search of PubMed, Scopus, Embase, and Google Scholar was conducted using the specified search strategy. Eligibility criteria included cases with miliary lesions in the brain confirmed through neuroimaging and various diagnostic procedures.
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